Cellular mechanisms of nicotine addiction

JA Dani, M De Biasi - Pharmacology Biochemistry and Behavior, 2001 - Elsevier
In developed countries, tobacco use is estimated to be the largest single cause of premature
death [Lancet 339 (1992) 1268]. Nicotine is the main addictive component of tobacco that …

Overview of nicotinic receptors and their roles in the central nervous system

JA Dani - Biological psychiatry, 2001 - Elsevier
Alzheimer's disease is a complex disorder affecting multiple neurotransmitters. In particular,
the degenerative progression is associated with loss within the cholinergic systems. It …

Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes

JR Genzen, W Van Cleve… - Journal of …, 2001 - journals.physiology.org
Although nicotinic agonists can modulate sensory transmission, particularly nociceptive
signaling, remarkably little is known about the functional expression of nicotinic …

Ligand-gated ion channels

GL Westbrook - Cell Physiology Source Book, 2001 - Elsevier
Publisher Summary This chapter discusses ligand-gated ion channels, which are membrane
proteins that are fundamental signaling molecules in neurons. The chapter is divided into …

[图书][B] Development of antigens used to make specific antibodies that differentiate two alpha subunits of nicotinic acetylcholine receptors in Aplysia californica

EL Garcia - 2001 - search.proquest.com
The nicotinic acetylcholine receptor (nAChR) is an ion channel composed of five protein
subunits, two of which are designated a subunits that bind the neurotransmitter …