The expanding field of psychoneuroimmunology has markedly increased knowledge about
the interference of the central nervous system and the immune system. Immunological …

Clues as to why long-lived species live so much longer than short-lived species may reside
in the amount of reactive oxygen species (ROS) produced and their effect on damaging cell …

Background A reduction in the relative lymphocyte count is a marker of the stress response;
however, its prognostic value remains undetermined. The objective of this study was to …

To elucidate the suppressive effects of energy restriction on the inflammatory responses to
lipopolysaccharide (LPS), mice were divided into a control group (fed 5.0 g diet/d; 71 kJ/d) …

Adrenal and gonadal steroids have protective effects on the skeleton that may be conferred
partly by their ability to inhibit bone resorptive cytokines such as interleukin 6 (IL-6). We …

Background. Cachexia is associated with elevated levels of cytokines in cancer and human
immunodeficiency virus patients. Studies in cancer and acquired immunodeficiency …

Using a variety of experimental rodent and human models, age-related alterations in
cytokine production by immune cells have been described extensively. While the precise …

Several studies have demonstrated that inhibitors of cyclooxygenase (COX) attenuate
various neuronal injuries and age-dependent demented conditions. From these findings, we …

Aging is accompanied by marked changes of steroid hormone levels which vary among
women and men. The age-related increase of cytokines such as interleukin (IL)-6 may …

The function of chemokines in promoting and modulating leukocyte migration is essential for
a prompt and efficacious inflammatory response and in host defence against infections. In …