Transition metals such as copper are essential for many physiological processes yet can be
toxic at elevated levels. Other metals (eg lead) are nonessential and potentially highly toxic …

The last ten years have witnessed major advances in our understanding of zinc transporters
and their regulation in eukaryotic organisms. Two families of transporters, the ZIP (Zrt-, I rt …

Uptake and translocation of cationic nutrients play essential roles in physiological processes
including plant growth, nutrition, signal transduction, and development. Approximately 5% of …

A total of 45 genes encoding for P-type ATPases have been identified in the complete
genome sequence of Arabidopsis. Thus, this plant harbors a primary transport capability not …

Heavy metal hyperaccumulation in plants is an intriguing and poorly understood
phenomenon. Transmembrane metal transporters are assumed to play a key role in this …

The brain barrier system, ie, the blood-brain and blood-cerebrospinal fluid barriers, is
important for zinc homeostasis in the brain. Zinc is supplied to the brain via both barriers. A …

Iron uptake from the soil is a tightly controlled process in plant roots, involving specialized
transporters. One such transporter, IRT1, was identified in Arabidopsis thaliana and shown …

The ZIP superfamily of transporters plays important roles in metal ion uptake in diverse
organisms. There are 12 ZIP-encoding genes in humans, and we hypothesize that many of …

Uptake kinetics and translocation characteristics of cadmium and zinc are presented for two
contrasting ecotypes of the Cd/Zn hyperaccumulator Thlaspi caerulescens, Ganges …

Although iron deficiency poses severe nutritional problems to crop plants, to date iron
transporters have only been characterized from the model plant Arabidopsis thaliana. To …