Regulation of the natural killer cell receptor repertoire
Natural killer cells express inhibitory receptors specific for MHC class I proteins and
stimulatory receptors with diverse specificities. The MHC-specific receptors discriminate …
stimulatory receptors with diverse specificities. The MHC-specific receptors discriminate …
Expression and function of NK cell receptors in CD8+ T cells
CW McMahon, DH Raulet - Current opinion in immunology, 2001 - Elsevier
A wide variety of inhibitory and stimulatory NK cell receptors are expressed by some CD8+
cytotoxic T lymphocytes in mice and humans. Recent data address the induction of these …
cytotoxic T lymphocytes in mice and humans. Recent data address the induction of these …
Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo
Subsets of natural killer (NK) cells are characterized by the expression of inhibitory and/or
stimulatory receptors specific for major histocompatibility complex (MHC) class I …
stimulatory receptors specific for major histocompatibility complex (MHC) class I …
Face off—the interplay between activating and inhibitory immune receptors
LL Lanier - Current opinion in immunology, 2001 - Elsevier
The function of leukocytes is regulated by the integration of positive and negative signals
received through cell surface receptors. Related receptors with similar extracellular domains …
received through cell surface receptors. Related receptors with similar extracellular domains …
Acquisition of external major histocompatibility complex class I molecules by natural killer cells expressing inhibitory Ly49 receptors
A Sjöström, M Eriksson, C Cerboni… - The Journal of …, 2001 - rupress.org
Murine natural killer (NK) cells express inhibitory Ly49 receptors specific for major
histocompatibility complex (MHC) class I molecules. We report that during interactions with …
histocompatibility complex (MHC) class I molecules. We report that during interactions with …
H-2D Ligand Expression by Ly49A+ Natural Killer (NK) Cells Precludes Ligand Uptake from Environmental Cells: Implications for NK Cell Function
To study the adaptation of natural killer (NK) cells to their major histocompatibility complex
(MHC) class I environment we have established a novel mouse model with mosaic …
(MHC) class I environment we have established a novel mouse model with mosaic …
Class I MHC-binding characteristics of the 129/J Ly49 repertoire
AP Makrigiannis, AT Pau, A Saleh… - The Journal of …, 2001 - journals.aai.org
The Ly49 family of NK cell receptors and its MHC-binding characteristics have only been
well characterized in C57BL/6 (B6) mice. Previous studies have shown that 129/J mice …
well characterized in C57BL/6 (B6) mice. Previous studies have shown that 129/J mice …
Expression of inhibitory" killer cell lectin‐like receptor G1" identifies unique subpopulations of effector and memory CD8 T cells
NB Beyersdorf, X Ding, K Karp… - European journal of …, 2001 - Wiley Online Library
T cell and natural killer (NK) cell functions are regulated by triggering of activating and
inhibitory cell surface receptors. Here, we have studied the expression profile and predicted …
inhibitory cell surface receptors. Here, we have studied the expression profile and predicted …
Expression of Ly49E and CD94/NKG2 on fetal and adult NK cells
K Van Beneden, F Stevenaert, A De Creus… - The Journal of …, 2001 - journals.aai.org
Murine NK cells express inhibitory receptors belonging to the Ly49 and CD94/NKG2 family.
Ly49E and CD94 are the only NK cell receptor transcripts detectable in fetal NK cells. Still …
Ly49E and CD94 are the only NK cell receptor transcripts detectable in fetal NK cells. Still …
The functional binding site for the C-type lectin–like natural killer cell receptor Ly49a spans three domains of its major histocompatibility complex class I ligand
N Matsumoto, M Mitsuki, K Tajima… - The Journal of …, 2001 - rupress.org
Natural killer (NK) cells express receptors that recognize major histocompatibility complex
(MHC) class I molecules and regulate cytotoxicity of target cells. In this study, we …
(MHC) class I molecules and regulate cytotoxicity of target cells. In this study, we …