Acute lung injury occurs as a result of a cascade of cellular events initiated by either
infectious or noninfectious inflammatory stimuli. An elevated level of proinflammatory …

Paediatric cardiac surgery often requires cardiopulmonary bypass (CPB) during the surgical
intervention. CPB is known to elicit a systemic inflammatory response with activation of the …

Recent clinical trials have shown that the survival of patients with acute respiratory distress
syndrome (ARDS) is improved by ventilation with reduced volumes. These studies …

Activated neutrophils contribute to the development and severity of acute lung injury (ALI).
Phosphoinositide 3-kinases (PI3-K) and the downstream serine/threonine kinase Akt/protein …

Protein tyrosine kinase (PTK) inhibitors have been proposed to reduce lung injury and lethal
toxicity. The mechanisms responsible for the effects of PTK inhibitors remain obscure. The …

The airway epithelium is injured by oxidants inhaled as atmospheric pollutants or produced
during inflammatory responses. We studied the effect of modulating the antioxidant …

Antioxidant therapy may be useful in diseases with impaired oxidant-antioxidant balance
such as pulmonary fibrosis. This study examines the effect of N-acetylcysteine (NAC) on …

Cysteine metabolism and whole blood glutathione synthesis in... : Critical Care Medicine
Cysteine metabolism and whole blood glutathione synthesis in septic pediatric patients …

The potential benefits of a high fruit and vegetable intake on the antioxidant status and on
relevant biomarkers of oxidative damage to lipids, proteins and DNA and on (functional) …

Reactivation of cytomegalovirus (CMV) from latency is a frequent complication of organ
transplantation, and the molecular mechanism by which this occurs is unknown. Previous …