A profile of fertilization in mammals

PM Wassarman, L Jovine, ES Litscher - Nature cell biology, 2001 - nature.com
Fertilization is defined as the process of union of two gametes, eggs and sperm. When
mammalian eggs and sperm come into contact in the female oviduct, a series of steps is set …

Galactosyltransferase function during mammalian fertilization

B Nixon, Q Lu, MJ Wassler, CI Foote, MA Ensslin… - Cells Tissues …, 2001 - karger.com
Gamete recognition has been studied extensively in the mouse. In this system, it is generally
believed that sperm bind to a class of O-linked oligosaccharides on the zona pellucida …

Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization

E Howes, JC Pascall, W Engel… - Journal of cell …, 2001 - journals.biologists.com
The mouse zona pellucida glycoprotein, mZP2, is thought to be the secondary receptor on
eggs for retention of acrosome-reacted sperm during fertilization. Here, we present evidence …

Cluster of genes encoding the major egg envelope protein of zebrafish

DE Mold, IF Kim, CM Tsai, D Lee… - Molecular …, 2001 - Wiley Online Library
The proteins of fish egg envelopes are encoded by genes that are closely related to the
genes for human zona pellucida proteins. A cluster of three genes coding for an egg …

Sulfogalactosylglycerolipid is involved in human gamete interaction

W Weerachatyanukul… - Molecular …, 2001 - Wiley Online Library
Recent results from our laboratory have revealed the role of sulfogalactosylglycerolipid
(SGG) in mouse sperm‐zona pellucida (ZP) binding. In this report, we demonstrated the …

A hatching enzyme substrate in the Xenopus laevis egg envelope is a high molecular weight ZPA homolog

LAL Lindsay, MA Wallace… - Development, growth & …, 2001 - Wiley Online Library
The Xenopus laevis egg envelope is composed of six or more glycoproteins, three of which
have been cloned and identified as the mammalian homologs ZPA (ZP2), ZPB (ZP1) and …

[PDF][PDF] Association of egg zona pellucida glycoprotein mZP3 with sperm protein sp56 during fertilization in mice

N Cohen, PM Wassarman - International Journal of Developmental …, 2001 - ijdb.ehu.es
Purified mouse sperm receptor, a zona pellucida glycoprotein called mZP3, binds to plasma
membrane overlying acrosome-intact sperm heads (PM Wassarman, 1999, Cell 96, 175 …

Immunohistochemical localization of zona pellucida proteins ZPA, ZPB and ZPC in human, cynomolgus monkey and mouse ovaries

U Eberspaecher, A Becker, P Bringmann… - Cell and Tissue …, 2001 - Springer
The zona pellucida of mammalian oocytes plays an important role in binding and activation
of sperm cells during the molecular events leading to fertilization. The genes coding for the …

A mouse acrosomal cortical matrix protein, MC41, has ZP2-binding activity and forms a complex with a 75-kDa serine protease

I Tanii, T Oh-oka, K Yoshinaga, K Toshimori - Developmental biology, 2001 - Elsevier
Sperm with a large acrosome such as that of guinea pigs and hamsters have a subdomain
structure in the anterior acrosome, but the mouse acrosome looks homogeneous and its …

Purified and Refolded Recombinant Bonnet Monkey (Macaca radiata) Zona Pellucida Glycoprotein-B Expressed in Escherichia coli Binds to Spermatozoa

CK Govind, GK Gahlay, S Choudhury… - Biology of …, 2001 - academic.oup.com
Bonnet monkey (Macaca radiata) zona pellucida glycoprotein-B (bmZPB), excluding the N-
terminal signal sequence and the C-terminus transmembrane-like domain, has been …