Chemokines facilitate leukocyte migration and positioning as well as other processes such
as angiogenesis and leukocyte degranulation. The burgeoning knowledge on chemokines …

HIV virus particles interact with several receptors on cell surfaces. Two receptors, CD4 and a
co-receptor act sequentially to trigger fusion of viral and cellular membranes and confer …

The chemokine receptors CCR2 and CCR5 play important roles in the recruitment of
monocytes/macrophages and T cells. To better understand the role of both receptors in …

Migration is a basic feature of many cell types in a wide range of species. Since the 1800s,
cell migration has been proposed to occur in the nervous and immune systems,, and distinct …

The chemokine superfamily of leukocyte chemo-attractants coordinates development and
deploy-ment of the immune system by signaling through a family of G protein–coupled …

Previously it was shown that the HHV-8-encoded chemokine receptor ORF74 shows
considerable agonist-independent, constitutive activity giving rise to oncogenic …

The human CXC chemokine receptor 4 (CXCR4) is a receptor for the chemokine stromal cell-
derived factor (SDF-1α) and a co-receptor for the entry of specific strains of human …

Infection with human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma (KS)-
associated herpesvirus, is necessary for the development of KS. The HHV-8 lytic-phase …

The murine cytomegalovirus CC chemokine homolog MCK-2 (m131-129) is an important
determinant of dissemination during primary infection. Reduced peak levels of viremia at …

Kaposi's sarcoma–associated herpesvirus (KSHV), the most recently discovered human
tumour virus, is the causative agent of Kaposi's sarcoma, primary effusion lymphoma and …