Multiple sclerosis: genomic rewards

JR Oksenberg, SE Baranzini, LF Barcellos… - Journal of …, 2001 - Elsevier
A large body of immunologic, epidemiologic, and genetic data indicate that tissue inury in
multiple sclerosis (MS) results from an abnormal immune response to one or more myelin …

Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia

MG Marrosu, R Murru, MR Murru… - Human molecular …, 2001 - academic.oup.com
Several studies have indicated that multiple sclerosis (MS) is associated and linked to the
major histocompatibility complex (MHC)/human leukocyte antigen (HLA) region of …

[PDF][PDF] Evidence of linkage with HLA-DR in DRB1* 15-negative families with multiple sclerosis

A Ligers, DA Dyment, CJ Willer, AD Sadovnick… - The American Journal of …, 2001 - cell.com
The importance of the HLA-DR locus to multiple sclerosis (MS) susceptibility was assessed
in 542 sib pairs with MS and in their families. By genotyping 1,978 individuals for HLA-DRB1 …

Analysis of an interferon-γ gene dinucleotide-repeat polymorphism in Nordic multiple sclerosis patients

Y Dai, T Masterman, WX Huang… - Multiple Sclerosis …, 2001 - journals.sagepub.com
The proinflammatory cytokine interferon (IFN)-γ has been shown to influence the course of
multiple sclerosis (MS). The IFN-γ (IFNG) contains a multiallelic dinucleotide repeat in intron …

[PDF][PDF] gene dinucleotide-repeat polymorphism in Nordic multiple sclerosis patients γ Analysis of an interferon

AS Soelberg-Sřrensen, J Hillert - academia.edu
The proinŻammatory cytokine interferon (IFN)-у has been shown to inŻuence the course of
multiple sclerosis (MS). The IFN-у (IFNG) contains a multiallelic dinucleotide repeat in intron …