Exhaled markers of pulmonary disease

SA Kharitonov, PJ Barnes - … journal of respiratory and critical care …, 2001 - atsjournals.org
There has recently been an explosion of interest in the analysis of breath constituents as a
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …

Conserved cAMP signaling cascades regulate fungal development and virulence

CA D'Souza, J Heitman - FEMS microbiology reviews, 2001 - academic.oup.com
Two well characterized signal transduction cascades regulating fungal development and
virulence are the MAP kinase and cAMP signaling cascades. Here we review the current …

Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans

GM Cox, HC McDade, SCA Chen… - Molecular …, 2001 - Wiley Online Library
The human pathogenic fungus Cryptococcus neoformans secretes a phospholipase enzyme
that demonstrates phospholipase B (PLB), lysophospholipase hydrolase and …

Aspects of fungal pathogenesis in humans

JAH van Burik, PT Magee - Annual Reviews in Microbiology, 2001 - annualreviews.org
▪ Abstract Fungal diseases have become increasingly important in the past few years.
Because few fungi are professional pathogens, fungal pathogenic mechanisms tend to be …

Intracellular parasitism of macrophages by Cryptococcus neoformans

M Feldmesser, S Tucker, A Casadevall - Trends in microbiology, 2001 - cell.com
Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …

Laccase of Cryptococcus neoformans Is a Cell Wall-Associated Virulence Factor

X Zhu, J Gibbons, J Garcia-Rivera… - Infection and …, 2001 - Am Soc Microbiol
Virulence is the outcome of an interaction between the host and a microbe and is
characterized by a large array of opposing reactions operating at the host-pathogen …

Could the urea cycle be translocating nitrogen in the arbuscular mycorrhizal symbiosis?

B Bago, P Pfeffer, Y Shachar-Hill - New Phytologist, 2001 - JSTOR
Arbuscular mycorrhizal (AM) fungi take up nitrogen from the soil, translocate it and transfer it
to the host plant (Jennings, 1995; Smith & Read, 1997), often in significant quantities …

Multiple virulence factors of Cryptococcus neoformans are dependent on VPH1

T Erickson, L Liu, A Gueyikian, X Zhu… - Molecular …, 2001 - Wiley Online Library
Acidification of vesicular compartments plays an important role in a number of cellular
transport processes, including protein secretion, metal cofactor insertion, glycosylation and …

Fungal virulence studies come of age

FC Odds, NAR Gow, AJP Brown - Genome biology, 2001 - Springer
Sophisticated molecular biological research has revealed many virulence attributes in at
least four pathogenic fungi, but the future study of fungal virulence requires investigators to …

Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase‐encoding gene, MAN1, and its impact on pathogenicity

EA Wills, IS Roberts, M Del Poeta, J Rivera… - Molecular …, 2001 - Wiley Online Library
The polysaccharide capsule surrounding Cryptococcus neoformans comprises manose,
xylose and glucuronic acid, of which mannose is the major constituent. The GDP‐mannose …