The human dopamine transporter gene: gene organization, transcriptional regulation, and potential involvement in neuropsychiatric disorders

MJ Bannon, SK Michelhaugh, J Wang… - European …, 2001 - Elsevier
The dopamine transporter is a plasma membrane protein that controls the spatial and
temporal domains of dopamine neurotransmission through the accumulation of extracellular …

The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression

S Fuke, S Suo, N Takahashi, H Koike… - The …, 2001 - nature.com
The human dopamine transporter (DAT1) gene contains a variable number of tandem
repeats (VNTR) in its 3′-untranslated region (UTR). The linkage and association between …

Association study of a dopamine transporter polymorphism and attention deficit hyperactivity disorder in UK and Turkish samples

S Curran, J Mill, E Tahir, L Kent, S Richards… - Molecular …, 2001 - nature.com
Molecular genetic studies in attention deficit hyperactivity disorder (ADHD) have focussed
on candidate genes within the dopamine system, which is thought to be the main site of …

The dopamine transporter gene (SLC6A3) variable number of tandem repeats domain enhances transcription in dopamine neurons

SK Michelhaugh, C Fiskerstrand… - Journal of …, 2001 - Wiley Online Library
The dopamine (DAT) and serotonin (SERT) transporter genes both contain variable number
of tandem repeats (VNTR) in non‐coding gene regions which have been correlated with a …

The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype …

D Martinez, J Gelernter, A Abi-Dargham… - …, 2001 - Elsevier
A 40 base polymorphism of a variable number of tandem repeats (VNTR) has been
described in the 3′ untranslated region of the gene (SLC6A3) coding for the dopamine …

Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder

TA Greenwood, M Alexander, PE Keck… - American journal of …, 2001 - Wiley Online Library
A role for the dopamine transporter (DAT) in bipolar disorder is implicated by several lines of
pharmacological evidence, as well as suggestive evidence of linkage at this locus, which we …

Two dopamine genes related to reports of childhood retrospective inattention and conduct disorder symptoms

DC Rowe, C Stever, D Chase, S Sherman… - Molecular …, 2001 - nature.com
The 7-repeat allele of the dopamine receptor D4 gene (DRD4) and the 10 repeat allele of
the dopamine transporter gene (DAT1) have shown association and linkage with symptoms …

Neurochemical investigation of the schizophrenic brain by in vivo phosphorus magnetic resonance spectroscopy

H Fukuzako - The World Journal of Biological Psychiatry, 2001 - Taylor & Francis
Abnormal phospholipid metabolisms may play important roles in the pathophysiology of
schizophrenia. Phosphorus magnetic resonance spectroscopy (31P-MRS) offers a new …

Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity

GM Miller, SM Yatin, R De La Garza II, M Goulet… - Molecular brain …, 2001 - Elsevier
We used RT–PCR to clone monoamine transporters from Macaca mulatta, Macaca
fasicularis and Saimiri sciureus (dopamine transporter; DAT) and Macaca mulatta …

Measurement of the striatal dopamine transporter density and heterogeneity in type 1 alcoholics using human whole hemisphere autoradiography

E Tupala, JT Kuikka, H Hall, K Bergström, T Särkioja… - Neuroimage, 2001 - Elsevier
Dopaminergic mechanisms are involved in the positive reinforcing and addicting effects of
alcohol. Positron emission tomography (PET) and single photon emission tomography …