Relationship of spikes, synaptic activity, and local changes of cerebral blood flow

M Lauritzen - Journal of Cerebral Blood Flow & Metabolism, 2001 - journals.sagepub.com
The coupling of electrical activity in the brain to changes in cerebral blood flow (CBF) is of
interest because hemodynamic changes are used to track brain function. Recent studies …

Dynamic imaging of cerebral blood flow using laser speckle

AK Dunn, H Bolay, MA Moskowitz… - Journal of Cerebral …, 2001 - journals.sagepub.com
A method for dynamic, high-resolution cerebral blood flow (CBF) imaging is presented in this
article. By illuminating the cortex with laser light and imaging the resulting speckle pattern …

NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat

Z Zhao, M Cheng, KR Maples, JY Ma, AM Buchan - Brain research, 2001 - Elsevier
Free radicals have gained wide acceptance as mediators of cerebral ischemic injury. It has
previously been reported that a spin trap nitrone, α-phenyl-N-tert-butyl nitrone (PBN), can …

Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats

N Tsuzuki, T Miyazawa, K Matsumoto… - Neurological …, 2001 - Taylor & Francis
Hepatocyte growth factor (HGF) was originally discovered as a powerful mitogen for
hepatocytes. HGF also has been reported to function as a neurotrophic factor as well as an …

Spontaneous and stimulus-evoked intrinsic optical signals in primary auditory cortex of the cat

MW Spitzer, MB Calford, JC Clarey… - Journal of …, 2001 - journals.physiology.org
Spontaneous and tone-evoked changes in light reflectance were recorded from primary
auditory cortex (A1) of anesthetized cats (barbiturate induction, ketamine maintenance) …

A new model of localized ischemia in rat somatosensory cortex produced by cortical compression

S Watanabe, JR Hoffman, RL Craik, PJ Hand, SE Croul… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—Because of its precise connectivity and functional specificity, the
rat whisker-barrel system offers an excellent opportunity to study experience-dependent …

Cerebral ischaemia in experimental cardiopulmonary resuscitation—comparison of epinephrine and aortic occlusion

R Gedeborg, C Hans, S Rubertsson, L Wiklund - Resuscitation, 2001 - Elsevier
The apparent inability of epinephrine to improve outcome after cardiopulmonary
resuscitation (CPR) could be caused by direct negative effects on the cerebral circulation …

Progressive and reproducible focal cortical ischemia with or without late spontaneous reperfusion generated by a ring-shaped, laser-driven photothrombotic lesion in …

XL Hu, P Wester, T Brännström, BD Watson… - Brain Research …, 2001 - Elsevier
Clinical stroke is mostly of thromboembolic origin, in which the magnitude of brain damage
resulting from arterial occlusions depends on the degree and duration of the concomitant …

Pre-treatment with candesartan protects from cerebral ischaemia

T Ito, Y Nishimura, J Saavedra - Journal of the Renin …, 2001 - journals.sagepub.com
Angiotensin II (Ang II) regulates cerebral blood flow by stimulating cerebral vasoconstriction
via AT1receptors. In adult spontaneously hypertensive rats (SHR), the cerebrovascular …

The effects of graded hypercapnia on the activation flow coupling response due to forepaw stimulation in α-chloralose anesthetized rats

BM Ances, JH Greenberg, JA Detre - Brain research, 2001 - Elsevier
Activation flow coupling (AFC), changes in cerebral blood flow (CBF) due to changes in
neural activity with functional stimulation, provides the physiological basis of many …