Albumin is the main determinant of plasma oncotic pressure and it plays a pivotal role in
modulating the distribution of fluids between compartments. Moreover, it has many other …

Hypertonic Saline Resuscitation of Hemorrhagic Shock Diminis... : Annals of Surgery
Hypertonic Saline Resuscitation of Hemorrhagic Shock Diminishes Neutrophil Rolling and …

In this study we aimed to examine the association between serum albumin concentration
and mortality risk in critically ill patients. We retrospectively studied 1003 patients admitted to …

Background The standard lactated Ringer's (LR) solution contains racemic lactate, an equal
mixture of d (−)-and l (+)-isomers. The aim of this study was to investigate whether racemic …

Background The Institute of Medicine has recommended intraosseous (IO) infusion of 7.5%
hypertonic saline (HTS) for combat casualties in shock. We tested the safety and efficacy of …

The aim of this study was to characterize gene expression following hemorrhagic shock and
resuscitation with emphasis on the differences between various resuscitation strategies …

Background Resuscitation from hemorrhagic shock causes profound immunologic changes.
The tonicity of fluids used for resuscitation clearly influences the immune response. Our …

The review by Oliveira and colleagues on the subject of hypertonic saline resuscitation in
sepsis (included in the present issue) suggests possible benefits for hypertonic saline. There …

Background. Polymorphonuclear neutrophil (PMN) sequestration in the lung is a hallmark of
acute respiratory distress syndrome (ARDS). We have shown that 25% Albumin (A25) …

Modern trauma management has recognized the importance of using conservative fluid
resuscitation regimes in order to prevent complications from fluid overload arising …