Borrowing concepts from the schema theory of genetic algorithms, we have developed a
computational algorithm to identify the fragments of proteins, or schemas, that can be …

The bottom-up approach to understanding the evolution of organisms is by studying
molecular evolution. With the large number of protein structures identified in the past …

Fibritin is a segmented coiled‐coil homotrimer of the 486‐residue product of phage T4 gene
wac. This protein attaches to a phage particle by the N‐terminal region and forms fibrous …

Temperature‐induced unfolding of Escherichia coli dihydrofolate reductase was carried out
by using molecular dynamic simulations. The simulations show that the unfolding generally …

Here we present a comparison between protein fragments produced by limited proteolysis
and those identified by computational cutting based on the building block folding model. The …

Calmodulin, the Ca2+-dependent activator of many cellular processes, contains two well-
defined structural domains, each of which binds two Ca2+ ions. In its Ca2+-free (apo) form, it …

In response to the criticism by A. Finkelstein (J. Biomol. Struct. Dyn. 20, 311–314, 2002) of
our Communication (J. Biomol. Struct. Dyn. 20, 5–6, 2002) several issues are dealt with …

The position independent dipole membrane proteins need to be oriented in the membrane
in order to function as channels, transporters or recognition systems. Membrane proteins …

To fold an amino acid chain into its three dimensional structure is a computationally huge
effort, requiring an enormous amount of time. To reduce the time required in such an …

Abstract Shikimate kinase (SK; EC 2.7. 1.71), an enzyme that catalyses the specific
phosphorylation of the 3-hydroxyl group of shikimate using ATP as the phosphoryl donor …