Get a ligand, get a life: integrins, signaling and cell survival

DG Stupack, DA Cheresh - Journal of cell science, 2002 - journals.biologists.com
Programmed cell death is crucial for the development and maintenance of multicellular
organisms. The decision to live, or to die, depends, at the cellular level, upon the cell's …

ANGPTL3 stimulates endothelial cell adhesion and migration via integrin αvβ3 and induces blood vessel formation in vivo

G Camenisch, MT Pisabarro, D Sherman… - Journal of Biological …, 2002 - ASBMB
The angiopoietin family of secreted factors is functionally defined by the C-terminal
fibrinogen (FBN)-like domain, which mediates binding to the Tie2 receptor and thereby …

Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins αvβ3 and α6β1 in human umbilical vein endothelial cells

SJ Leu, SCT Lam, LF Lau - Journal of Biological Chemistry, 2002 - ASBMB
CYR61 (CCN1) is an extracellular matrix-associated protein of the CCN family, which also
includes CTGF (CCN2), NOV (CCN3), WISP-1 (CCN4), WISP-2 (CCN5), and WISP-3 …

Integrin αvβ3 expression confers on tumor cells a greater propensity to metastasize to bone

I Pecheur, O Peyruchaud, CM Serre… - The FASEB …, 2002 - Wiley Online Library
The reasons why tumor cells metastasize to bone remain obscure. There is some evidence
to support the theory that integrins (acting as cell surface adhesion receptors) play a role in …

Adenovirus encoding vascular endothelial growth factor–D induces tissue-specific vascular patterns in vivo

TV Byzova, CK Goldman, J Jankau… - Blood, The Journal …, 2002 - ashpublications.org
The capacity of an adenovirus encoding the mature form of vascular endothelial growth
factor (VEGF)–D, VEGF-DΔNΔC, to induce angiogenesis, lymphangiogenesis, or both was …

[PDF][PDF] Pro-angiogenic Activities of CYR61 (CCN1) Mediated through Integrins v 3 and 6 in Human Umbilical Vein Endothelial Cells

SJ Leu, CTL Stephen, LF Lau - breast cancer, 2002 - researchgate.net
CYR61 (CCN1) is an extracellular matrix-associated protein of the CCN family, which also
includes CTGF (CCN2), NOV (CCN3), WISP-1 (CCN4), WISP-2 (CCN5), and WISP-3 …

骨唾液蛋白与肿瘤骨转移

王捷, 张宏斌, 郑文岭 - 广东医学, 2002 - cqvip.com
骨唾液蛋白(bone sialoprotein, BSP) 是1972 年首先从牛骨皮质中分离出的一种富含唾液酸的
糖蛋白; 至今已从人, 牛, 兔和猪的骨中相继分离出该蛋白. 骨唾液蛋白主要由成骨细胞 …

Identification and functional characterization of novel receptor ligands of CD40 and alpha (v) beta (3) integrin: Implications for gene delivery

JL Richards - 2002 - search.proquest.com
Gene delivery to target tissues is often limited by the native tropism of the viral or non-viral
vector used. Failure to infect the target cell of choice may limit the use of an otherwise …

[图书][B] Organ-specific suppression of cancer metastasis

JF Harms - 2002 - search.proquest.com
Our lab previously showed that introduction of human chromosome 6 into the highly
metastatic human melanoma cell line, C8161, completely suppressed metastasis to lung …