[HTML][HTML] DNA methylation, imprinting and cancer
C Plass, PD Soloway - European Journal of Human Genetics, 2002 - nature.com
It is well known that a variety of genetic changes influence the development and progression
of cancer. These changes may result from inherited or spontaneous mutations that are not …
of cancer. These changes may result from inherited or spontaneous mutations that are not …
[HTML][HTML] Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene
DU Lee, S Agarwal, A Rao - Immunity, 2002 - cell.com
The relation of CpG methylation to gene silencing is well established, but the contribution of
DNA demethylation to gene expression during cell differentiation remains unclear. We show …
DNA demethylation to gene expression during cell differentiation remains unclear. We show …
5-Methylcytosine as a marker for the monitoring of DNA methylation
J Havliš, M Trbušek - Journal of Chromatography B, 2002 - Elsevier
The extent of the DNA methylation of genomic DNA as well as the methylation pattern of
many gene-regulatory areas are important aspects with regard to the state of genetic …
many gene-regulatory areas are important aspects with regard to the state of genetic …
Optimization of baculovirus-mediated expression and purification of hexahistidine-tagged murine DNA (cytosine-C5)-methyltransferase-1 in Spodoptera frugiperda 9 …
AS Brank, DM Van Bemmel, JK Christman - Protein expression and …, 2002 - Elsevier
Enzymatic DNA methylation of carbon 5 of cytosines is an epigenetic modification that plays
a role in regulating gene expression, differentiation, and tumorigenesis. DNA (cytosine-C5) …
a role in regulating gene expression, differentiation, and tumorigenesis. DNA (cytosine-C5) …
Utilization of antisense oligonucleotides to study the role of 5-cytosine DNA methyltransferase in cellular transformation and oncogenesis
M Szyf - Methods, 2002 - Elsevier
A large body of data point toward 5-cytosine DNA methyltransferase 1 (DNMT1) as a critical
component of oncogenic programs. The study of the role of DNMT1 in cancer has been …
component of oncogenic programs. The study of the role of DNMT1 in cancer has been …
DNA methylation machinery as molecular targets for cancer therapeutics
PM Campbell - 2002 - escholarship.mcgill.ca
One of the elements commonly seen in cancer is the change in methylation status of the
genome. These aberrations in methylation appear to be critical for the neoplastic phenotype …
genome. These aberrations in methylation appear to be critical for the neoplastic phenotype …