Glucose homeostasis is of paramount concern to the brain since glucose is its primary fuel.
Thus, the brain has evolved mechanisms to sense and respond to changes in glucose …

Dopaminergic (DA) midbrain neurons in the substantia nigra (SN) and ventral tegmental
area (VTA) are involved in various brain functions such as voluntary movement and reward …

Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response to
carbohydrate and fat in the diet. Despite the interest in GLP-1 as an antidiabetic agent, very …

Dopaminergic midbrain (DA) neurons display two principal activity patterns in vivo, single-
spike and burst firing, the latter coding for reward-related events. We have shown recently …

Glucose is a critical substrate for brain and organ function. Specialized glucosensing
neurons, which are involved in the control of energy homeostasis and neuroendocrine …

The real‐time quantitative polymerase chain reaction (rtqPCR) has overcome the limitations
of conventional, time‐consuming quantitative PCR strategies and is maturing into a routine …

Guanidinoacetate methyltransferase (GAMT) deficiency is an autosomal recessively
inherited disorder of creatine biosynthesis. The disease occurs in early life with …

ATP-sensitive potassium (KATP) channels are known to be critical in the control of both
insulin and glucagon secretion, the major hormones in the maintenance of glucose …

Kir6. 2, a subunit of the ATP-sensitive K+ channel (KATP), was localized in adult rat brain by
immunohistochemistry and in situ hybridization. The Kir6. 2 mRNA was widely expressed in …

Enteroendocrine (EE) cells represent complex, rare, and diffusely‐distributed intestinal
epithelial cells making them difficult to study in vivo. A specific sub‐population of EE cells …