Recent evidence has implicated galectins and their ligands as master regulators of immune
cell homeostasis. Whereas some members of this family, such as galectin-3, behave as …

Galectins are members of a highly conserved family of β-galactoside-binding animal lectins.
Presently, more than 14 members have been identified and additional homologues are …

Galectin-3 is a multifunctional oncogenic protein found in the nucleus and cytoplasm and
also the extracellular milieu. Although recent studies demonstrated an anti-apoptotic activity …

Control of cell death is critical in eukaryotic development, immune system homeostasis, and
control of tumorigenesis. The galectin family of lectins is implicated in all of these processes …

Galectins and their ligands have been implicated in cell transformation and cancer
metastasis, and found to have prognostic value. Mac-2 BP, also known as 90K, is a highly …

Galectin-3 is a multifunctional carbohydrate-binding protein found in the nucleus, cytoplasm
and the extracellular milieu. Nuclear galectin-3 expression is associated with cell …

We investigated the mechanisms underlying the pro-apoptotic activity exerted by oxidized
low-density lipoproteins (oxLDL) in Caco-2 intestinal cells, a cell line which retains many …

Galectins are a large family of structurally related β-galactoside-binding proteins that play a
pivotal role in the control of cell differentiation, proliferation, activation and apoptosis of many …

We investigated the role of galectin-3 in metastasis of human breast carcinoma BT549 cells
using the experimental liver metastasis model. Underlying mechanisms were then …

Over the last decade, we have witnessed an explosion of information regarding the function
of glycoconjugates, carbohydrate-binding proteins, and the elucidation of the sugar code …