The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function
L Joos, JQ He, MB Shepherdson… - Human molecular …, 2002 - academic.oup.com
The matrix metalloproteinases (MMPs) comprise a family of at least 20 proteolytic enzymes
that play an essential role in tissue remodeling. MMP1 (interstitial collagenase), MMP9 …
that play an essential role in tissue remodeling. MMP1 (interstitial collagenase), MMP9 …
Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease
N Lamblin, C Bauters, X Hermant, JM Lablanche… - Journal of the American …, 2002 - jacc.org
Objectives: Our hypothesis was that functional polymorphisms in matrix metalloproteinase
(MMP) genes may act as susceptibility factors for the development of coronary aneurysms …
(MMP) genes may act as susceptibility factors for the development of coronary aneurysms …
The role of matrix metalloproteinases in vascular disease
IM Loftus, MM Thompson - Vascular Medicine, 2002 - journals.sagepub.com
There is growing interest in the role of matrix metalloproteinasesin vascular diseases. These
conditions are often characterized by excessive tissue remodelling, and increased matrix …
conditions are often characterized by excessive tissue remodelling, and increased matrix …
A polymorphism in the matrix metalloproteinase-9 promoter is associated with increased risk of preterm premature rupture of membranes in African Americans
PE Ferrand, S Parry, M Sammel… - Molecular human …, 2002 - academic.oup.com
Fetal membrane rupture is associated with increased expression of matrix metalloproteinase-
9 (MMP-9) and matrix degradation. We have determined the functional significance of a …
9 (MMP-9) and matrix degradation. We have determined the functional significance of a …
Increased expression of phosphorylated c-Jun amino-terminal kinase and phosphorylated c-Jun in human cerebral aneurysms: role of the c-Jun amino-terminal …
Y Takagi, M Ishikawa, K Nozaki, S Yoshimura… - …, 2002 - journals.lww.com
OBJECTIVE: Vascular remodeling via apoptotic mechanisms is an important factor in
vascular diseases. c-Jun amino-terminal kinase (JNK) is a member of the mitogen-activated …
vascular diseases. c-Jun amino-terminal kinase (JNK) is a member of the mitogen-activated …
Association of a decreased number of d (CA) repeats in the matrix metalloproteinase-9 promoter with glomerulosclerosis susceptibility in mice
A Fornoni, Y Wang, O Lenz, LJ Striker… - Journal of the American …, 2002 - journals.lww.com
The genetic background plays an important role in the development of progressive
glomerulosclerosis. However, no marker is available for the reliable prediction of genetic …
glomerulosclerosis. However, no marker is available for the reliable prediction of genetic …
Gelatinase B, PECAM-1 and MCP-3 gene polymorphisms in Belgian multiple sclerosis
I Nelissen, B Dubois, A Goris, I Ronsse… - Journal of the …, 2002 - Elsevier
Polymorphic microsatellite markers in the genes for gelatinase B, PECAM-1 and MCP-3
have previously been analysed in Swedish and Sardinian individuals to test for association …
have previously been analysed in Swedish and Sardinian individuals to test for association …
Genetics of intracranial aneurysm
D Woo, J Broderick - Seminars in Cerebrovascular Diseases and Stroke, 2002 - Elsevier
Subarachnoid hemorrhage (SAH) secondary to ruptured saccular intracranial aneurysm (IA)
is a complex trait, with both genetic and environmental risk factors playing an important part …
is a complex trait, with both genetic and environmental risk factors playing an important part …
Multiple Intracranial Aneurysms: Angiographic Study and Endovascular Treatment
F Mont'Alverne, A Tournade… - Interventional …, 2002 - journals.sagepub.com
We evaluate endovascular treatment (EVT) as an option to deal with multiple intracranial
aneurysms (MA). From 1994 to 2001, 24 patients underwent EVT for 59 MA. Patients were …
aneurysms (MA). From 1994 to 2001, 24 patients underwent EVT for 59 MA. Patients were …
The roles of MMPs for cerebral aneurysm formation
M Morimoto, N Kume, S Miyamoto, A Mizoguchi… - … Medical Science Against …, 2002 - Springer
Cerebral aneurysm (CA) is histologically characterized by fragmentation of the internal
elastic lamina and thinning of the medial smooth muscle cell layer. Its occurrence can be …
elastic lamina and thinning of the medial smooth muscle cell layer. Its occurrence can be …