Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells

F Borrego, J Kabat, DK Kim, L Lieto, K Maasho… - Molecular …, 2002 - Elsevier
Natural killer (NK) cells express receptors that are specific for MHC class I molecules. These
receptors play a crucial role in regulating the lytic and cytokine expression capabilities of NK …

Tetrameric complexes of HLA-E, HLA-F, and HLA-G

DSJ Allan, EJM Lepin, VM Braud… - Journal of …, 2002 - Elsevier
HLA-E, HLA-F, and HLA-G are human nonclassical MHC class Ib molecules. To study the
function and identify potential ligands of these molecules, we constructed tetrameric …

Decidual macrophages are potentially susceptible to inhibition by class Ia and class Ib HLA molecules

MG Petroff, P Sedlmayr, D Azzola, JS Hunt - Journal of reproductive …, 2002 - Elsevier
Several members of the immunoglobulin-like transcript (ILT), also called leukocyte
immunoglobulin-like receptor (LIR), family of transmembrane proteins have been identified …

Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction

GM Spaggiari, P Contini, A Dondero… - Blood, The Journal …, 2002 - ashpublications.org
The engagement of the activating isoforms of C-type lectin inhibitory receptor (CLIR) or killer
Ig-like receptor (KIR) by their natural ligands, represented by soluble HLA-I (sHLA-I) …

Mutational analysis of immunoreceptor tyrosine-based inhibition motifs of the Ig-like transcript 2 (CD85j) leukocyte receptor

T Bellón, F Kitzig, J Sayós… - The Journal of …, 2002 - journals.aai.org
The inhibitory receptor Ig-like transcript (ILT) 2 (leukocyte Ig-like receptor or CD85j) is a type
I transmembrane protein expressed by different leukocyte lineages. The extracellular region …

Association of MR1 protein, an MHC class I-related molecule, with β2-microglobulin

H Yamaguchi, K Hashimoto - Biochemical and biophysical research …, 2002 - Elsevier
MR1 is a major histocompatibility complex (MHC) class I-related gene conserved among
mammals, and its predicted amino acid sequence is relatively closer to the classical MHC …

Genetically modified HLA class I molecules able to inhibit human NK cells without provoking alloreactive CD8+ CTLs

A Sharland, A Patel, JH Lee, AE Cestra… - The Journal of …, 2002 - journals.aai.org
Human NK cells are likely to be important effectors of xenograft rejection. Expression of HLA
class I molecules by transfected porcine cells can protect them from human NK cell …

Listing, location, binding motifs, and expression of nonclassical class I and related genes and molecules

J Forman, KF Lindahl - Current Protocols in Immunology, 2002 - Wiley Online Library
The tables presented in this appendix list nonclassical class I or related genes/molecules
arranged by the chromosomal region where they are encoded. This includes genes that fall …

[PDF][PDF] Soluble HLA class I induces NK cell apoptosis upon the engagement of

The engagement of the activating isoforms of C-type Lectin Inhibitory Receptor (CLIR) or
Killer Ig-like receptor (KIR) by their natural ligands, represented by soluble HLA-I (sHLA-I) …

[PDF][PDF] Genetically Modified HLA Class I Molecules

PA CD - J Immunol, 2002 - academia.edu
Human NK cells are likely to be important effectors of xenograft rejection. Expression of HLA
class I molecules by transfected porcine cells can protect them from human NK cell …