Laser and non-laser light sources for photodynamic therapy

L Brancaleon, H Moseley - Lasers in medical science, 2002 - Springer
Photodynamic therapy (PDT) is an anticancer combination therapy, which requires a
photosensitiser, which tends to accumulate preferentially in the tumour, and light. Historically …

[HTML][HTML] Optical non-invasive approaches to diagnosis of skin diseases

N Kollias, GN Stamatas - Journal of Investigative Dermatology Symposium …, 2002 - Elsevier
A number of noninvasive approaches have been developed over the years to provide
objective evaluation of the skin both in health and in disease. The advent of computers, as …

Optical properties of selected native and coagulated human brain tissues in vitro in the visible and near infrared spectral range

AN Yaroslavsky, PC Schulze… - Physics in Medicine …, 2002 - iopscience.iop.org
Medical laser applications require knowledge about the optical properties of target tissue. In
this study, the optical properties of selected native and coagulated human brain structures …

Imaging cells and extracellular matrix in vivo by using second-harmonic generation and two-photon excited fluorescence

A Zoumi, A Yeh, BJ Tromberg - Proceedings of the National …, 2002 - National Acad Sciences
Multiphoton microscopy relies on nonlinear light–matter interactions to provide contrast and
optical sectioning capability for high-resolution imaging. Most multiphoton microscopy …

NAD(P)H and Collagen as in Vivo Quantitative Fluorescent Biomarkers of Epithelial Precancerous Changes

I Georgakoudi, BC Jacobson, MG Muller, EE Sheets… - Cancer research, 2002 - AACR
During the development of neoplasia, epithelial tissues undergo biochemical and structural
changes that can manifest in tissue fluorescence. There have been several reports on …

Trimodal spectroscopy for the detection and characterization of cervical precancers in vivo

I Georgakoudi, EE Sheets, MG Müller… - American journal of …, 2002 - Elsevier
OBJECTIVE: The objective of this study was to assess the potential of 3 spectroscopic
techniques (intrinsic fluorescence, diffuse reflectance, and light scattering) individually and …

Autofluorescence endoscopy in the diagnosis of early laryngeal cancer and its precursor lesions

K Malzahn, T Dreyer, H Glanz, C Arens - The Laryngoscope, 2002 - Wiley Online Library
Objectives Because early detection and preoperative assessment of laryngeal cancer and
its precursor lesions are essential for curative and function‐preserving surgical treatment …

Quantitative fluorescence lifetime spectroscopy in turbid media: comparison of theoretical, experimental and computational methods

K Vishwanath, B Pogue, MA Mycek - Physics in Medicine & …, 2002 - iopscience.iop.org
A Monte Carlo model developed to simulate time-resolved fluorescence propagation in a
semi-infinite turbid medium was validated against previously reported theoretical and …

Realistic three-dimensional epithelial tissue phantoms for biomedical optics

K Sokolov, J Galvan, A Myakov, A Lacy… - … of biomedical optics, 2002 - spiedigitallibrary.org
We introduce new realistic three-dimensional tissue phantoms which can help to understand
the optical properties of human epithelium as well as the optical signatures associated with …

Fiber optic probe for polarized reflectance spectroscopy in vivo: Design and performance

A Myakov, L Nieman, L Wicky… - … of biomedical optics, 2002 - spiedigitallibrary.org
We present the design and construction of a fiber optic probe for elastic light scattering
spectroscopy in vivo with polarized excitation and polarization sensitive detection. The …