HIV entry inhibitors in clinical development

BM O'Hara, WC Olson - Current opinion in pharmacology, 2002 - Elsevier
Despite recent advances, present therapies for human immunodeficiency virus type 1 (HIV-
1) infection are limited by their failure to eradicate HIV-1, by the emergence of multidrug …

Mixed lineage kinase 3 mediates gp120IIIB‐induced neurotoxicity

A Bodner, AC Maroney, JP Finn… - Journal of …, 2002 - Wiley Online Library
Overexpression of gp120, the major coat protein of the HIV‐1 virus, in central glial cells, or
treatment of neurons with gp120 in culture, produces apoptotic neuronal death. Here we …

Restricted SIV replication in rhesus macaque lung tissues during the acute phase of infection

CL Fuller, YK Choi, BA Fallert, S Capuano III… - The American journal of …, 2002 - Elsevier
The extent to which simian immunodeficiency virus (SIV) replication in lung tissues
contributes to the pool of viruses replicating during acute infection is incompletely …

CD8+ T-cell immunity to HIV infection

P Piazza, Z Fan, CR Rinaldo - Clinics in laboratory medicine, 2002 - labmed.theclinics.com
Since the first cases were reported in the early 1980s, the AIDS epidemic has grown to
alarming proportions both in the United States and the rest of the world, particularly in sub …

Similar regulation of cell surface human T-cell leukemia virus type 1 (HTLV-1) surface binding proteins in cells highly and poorly transduced by HTLV-1-pseudotyped …

KS Jones, M Nath, C Petrow-Sadowski… - Journal of …, 2002 - Am Soc Microbiol
Little is known about the requirements for human T-cell leukemia virus type 1 (HTLV-1)
entry, including the identity of the cellular receptor (s). Previous studies have shown that …

[图书][B] Phylogenetic analysis of feline immunodeficiency virus and the development of a prophylactic genetic vaccine

EA Weaver - 2002 - search.proquest.com
Feline immunodeficiency virus (FIV) is a natural pathogen of domestic and wild cats. This
study investigates the use of DNA vectors capable of expressing FIV gag and envelope …

[图书][B] Analysis of target genes regulated by the PAX3-FKHR oncoprotein associated with alveolar rhabdomyosarcoma

O Tomescu - 2002 - search.proquest.com
The consistent association of hematopoietic and mesenchymal tumors with specific,
balanced chromosomal translocations that generate chimeric oncogenes implicates the …

Role of the leader sequence of human immunodeficiency virus type 1 in viral replication, genome dimerization, encapsidation, and proviral DNA synthesis

N Shen - 2002 - escholarship.mcgill.ca
Human immunodeficiency virus type 1 (HIV-1) genome consists of two identical RNAs that
appear noncovalently linked near their 5'ends. The 5'untranslated region is called leader …

[PDF][PDF] Bedeutung der N-Glykosylierung der Chemokinrezeptoren CXCR4 und CCR5 für die Infektion mit dem Humanem Immundefizienzvirus Typ-1

I Thordsen - 2002 - macau.uni-kiel.de
Das Humane Immundefizienzvirus Typ-1 (HIV-1) benötigt für die Infektion von Zellen die
Bindung an CD4 und die Interaktion mit den Chemokinrezeptoren CXCR4 oder CCR5 …