The insulin receptor (IR) occurs in two isoforms (IR-A and IR-B) resulting from alternative
splicing of exon 11 of the gene. The IR-A isoform is predominantly expressed in fetal tissues …

Galectin-3 is a protein of the lectin family that has been associated with neoplastic
processes in various tissues. In the thyroid, expression of this protein has been described in …

Methods. The 2 main scientific bibliographic databases queried in this study were the
Science Citation Index (SCI), which is a bibliographic database maintained by the Institute of …

Gene therapy may be an effective approach to thyroid carcinoma refractory to conventional
treatment. A transcriptionally targeted retroviral vector for gene therapy of thyroid carcinomas …

The majority of thyroid adenomas are of clonal origin. In a subset of toxic adenomas (TAs)
and cold nodules (CNs) activating mutations in the thyrotropin (TSH) receptor or G s-α gene …

MODERN advances in molecular technology have given us the chance to establish new
strategies to diagnose and treat cancer [1, 2]. In order to implement such molecular-based …

Highly specialized cells, the thyrocytes, express a thyroid-specific set of genes for
thyroglobulin (Tg), thyroperoxidase, and the transcription factors TTF-1, TTF-2, and Pax-8 …

Existen datos que nos permiten afirmar que probablemente, en gran parte de los casos, no
existe una solución de continuidad entre las diferentes neoplasias tiroideas de estirpe …

The product of the nm23 gene was held for a long time to be an important anti-metastatic
factor. We found, instead, in a group of well-characterized patients with thyroid carcinomas …

A vizsgálat célja: C-myc-és Ha-ras-amplifikáció ill. p53-deléció, valamint fokozott ciklin D1-,
p53-és p21-(WAF1) expresszió elôfordulásának és esetleges prognosztikai jelentôségének …