Electrospun nanofibrous structure: a novel scaffold for tissue engineering

WJ Li, CT Laurencin, EJ Caterson… - Journal of Biomedical …, 2002 - Wiley Online Library
The architecture of an engineered tissue substitute plays an important role in modulating
tissue growth. A novel poly (d, l‐lactide‐co‐glycolide)(PLGA) structure with a unique …

Tendon healing in a bone tunnel. Part II: Histologic analysis after biodegradable interference fit fixation in a model of anterior cruciate ligament reconstruction in sheep

A Weiler, RFG Hoffmann, HJ Bail, O Rehm… - Arthroscopy: the journal …, 2002 - Elsevier
Purpose: Tendon-to-bone healing of soft-tissue grafts has been described to progress by the
development of a fibrous interzone that undergoes a maturation process leading to the …

Fabrication of porous biodegradable polymer scaffolds using a solvent merging/particulate leaching method

CJ Liao, CF Chen, JH Chen, SF Chiang… - … Research: An Official …, 2002 - Wiley Online Library
This study developed a solvent merging/par‐ticulate leaching method for preparing three‐
dimensional porous scaffolds. Poly (l‐lactic‐co‐glycolic acid)(PLGA) and sodium chloride …

Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles

YN Konan, R Gurny, E Allémann - International journal of pharmaceutics, 2002 - Elsevier
The feasibility of producing sterile and freeze-dried polyester nanoparticles was
investigated. Various poly (d, l-lactide-co-glycolide) and poly (d, l-lactide) were selected as …

Study on the three-dimensional proliferation of rabbit articular cartilage-derived chondrocytes on polyhydroxyalkanoate scaffolds

Y Deng, K Zhao, X Zhang, P Hu, GQ Chen - Biomaterials, 2002 - Elsevier
Polymer scaffold systems consisting of poly (hydroxybutyrate-co-hydroxyhexanoate)(
PHBHHx)/polyhydroxybutyrate (PHB)(PHBHHx/PHB) were investigated for possible …

Alginate as a chondrocyte-delivery substance in combination with a non-woven scaffold for cartilage tissue engineering

WJCM Marijnissen, GJVM van Osch, J Aigner… - Biomaterials, 2002 - Elsevier
For tissue engineering of cartilage, chondrocytes can be seeded in a scaffold and stimulated
to produce a cartilage-like matrix. In the present study, we investigated the effect of alginate …

Insulin-loaded biodegradable PLGA microcapsules: initial burst release controlled by hydrophilic additives

Y Yamaguchi, M Takenaga, A Kitagawa… - Journal of Controlled …, 2002 - Elsevier
We investigated the controlled release of human insulin at an initial stage from poly (dl-lactic-
co-glycolic acid)(PLGA, Mw 6600) spherical matrices. PLGA microcapsules were prepared …

Preliminary report on the biocompatibility of a moldable, resorbable, composite bone graft consisting of calcium phosphate cement and poly (lactide‐co‐glycolide) …

CG Simon Jr, CA Khatri, SA Wight… - Journal of orthopaedic …, 2002 - Wiley Online Library
We have assessed the biocompatibility of a new composite bone graft consisting of calcium
phosphate cement (CPC) and poly (lactide‐co‐glycolide)(PLGA) microspheres …

Reduction of surface-induced inflammatory reaction on PLGA/MPC polymer blend

Y Iwasaki, S Sawada, K Ishihara, G Khang, HB Lee - Biomaterials, 2002 - Elsevier
Poly (lactide-co-glycolide)(PLGA) has been believed to be a good biocompatible material for
tissue engineering due to its biodegradability and non-toxicity of the monomer. However, the …

Synthesis, biodegradability, and biocompatibility of lysine diisocyanate–glucose polymers

JY Zhang, EJ Beckman, J Hu, GG Yang… - Tissue …, 2002 - liebertpub.com
The success of a tissue-engineering application depends on the use of suitable biomaterials
that degrade in a timely manner and induce the least immunogenicity in the host. With this …