Time in the biological sense is measured by cycles that range from milliseconds to years.
Circadian rhythms, which measure time on a scale of 24 h, are generated by one of the most …

The circadian rhythms in mammals are regulated by a pacemaker located in the
suprachiasmatic nucleus of the hypothalamus,. Four clock-gene families have been found to …

In mammals, circadian control of physiology and behavior is driven by a master pacemaker
located in the suprachiasmatic nuclei (SCN) of the hypothalamus. We have used gene …

The Period2 gene plays a key role in controlling circadian rhythm in mice. We report here
that mice deficient in the mPer2 gene are cancer prone. After γ radiation, these mice show a …

The suprachiasmatic nucleus (SCN) controls the circadian rhythm of physiological and
behavioural processes in mammals. Here we show that prokineticin 2 (PK2), a cysteine-rich …

Circadian rhythmicity in mammals is under the control of a molecular pacemaker constituted
of clock gene products organized in transcriptional autoregulatory loops. Phase resetting of …

Recent studies have shown that casein kinase I ε (CKIε) is an essential regulator of the
mammalian circadian clock. However, the detailed mechanisms by which CKIε regulates …

For many years, neurons of the suprachiasmatic nucleus (SCN) in the hypothalamus were
thought to contain the unique mammalian clock controlling circadian rhythmicity of …

In mammals, peripheral circadian clocks are present in most tissues, but little is known about
how these clocks are synchronized with the ambient 24-h cycles. By using rat-1 fibroblasts, a …

The brain's biological clock, which, in mammals, is located in the suprachiasmatic nucleus
(SCN), generates circadian rhythms in behaviour and physiology. These biological rhythms …