Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules
N Shastri, S Schwab, T Serwold - Annual review of immunology, 2002 - annualreviews.org
Gene-chips contain thousands of nucleotide sequences that allow simultaneous analysis of
the complex mixture of RNAs transcribed in cells. Like these gene-chips, major …
the complex mixture of RNAs transcribed in cells. Like these gene-chips, major …
Listeria monocytogenes: Clinical and Experimental Update
EJ Wing, SH Gregory - The Journal of infectious diseases, 2002 - academic.oup.com
Listeria monocytogenes, a small gram-positive bacillus, causes sepsis and meningitis in
immunocompromised patients and a devastating maternal/fetal infection in pregnant …
immunocompromised patients and a devastating maternal/fetal infection in pregnant …
Programmed contraction of CD8+ T cells after infection
VP Badovinac, BB Porter, JT Harty - Nature immunology, 2002 - nature.com
The extent of infection and rate of pathogen clearance are thought to determine both the
magnitude of antigen-specific CD8+ T cell expansion and the ensuing contraction to a stable …
magnitude of antigen-specific CD8+ T cell expansion and the ensuing contraction to a stable …
Immunodominance in Virus-Induced CD8+ T-Cell Responses Is Dramatically Modified by DNA Immunization and Is Regulated by Gamma Interferon
F Rodriguez, S Harkins, MK Slifka, JL Whitton - Journal of virology, 2002 - Am Soc Microbiol
The phenomenon whereby the host immune system responds to only a few of the many
possible epitopes in a foreign protein is termed immunodominance. Immunodominance …
possible epitopes in a foreign protein is termed immunodominance. Immunodominance …
Analysis of endogenous peptides bound by soluble MHC class I molecules: a novel approach for identifying tumor‐specific antigens
E Barnea, I Beer, R Patoka, T Ziv… - European journal of …, 2002 - Wiley Online Library
Abstract The Human MHC Project aims at comprehensive cataloging of peptides presented
within the context of different human leukocyte antigens (HLA) expressed by cells of various …
within the context of different human leukocyte antigens (HLA) expressed by cells of various …
Vaccination with Poly-l-Arginine As Immunostimulant for Peptide Vaccines: Induction of Potent and Long-Lasting T-Cell Responses against Cancer Antigens
F Mattner, JK Fleitmann, K Lingnau, W Schmidt… - Cancer research, 2002 - AACR
Vaccines that induce high numbers of sustained T cell responses are urgently needed for
the treatment of numerous diseases including cancer. Antigen-presenting cells (APCs), the …
the treatment of numerous diseases including cancer. Antigen-presenting cells (APCs), the …
Poly-L-arginine synergizes with oligodeoxynucleotides containing CpG-motifs (CpG-ODN) for enhanced and prolonged immune responses and prevents the CpG …
K Lingnau, A Egyed, C Schellack, F Mattner, M Buschle… - Vaccine, 2002 - Elsevier
This study describes an entirely synthetic vaccine composed of antigenic peptides (T cell
epitopes), oligodeoxynucleotides containing CpG-motifs (CpG-ODN) and poly-l-arginine …
epitopes), oligodeoxynucleotides containing CpG-motifs (CpG-ODN) and poly-l-arginine …
Genetic analysis of influences on survival following Toxoplasmagondii infection
J Johnson, Y Suzuki, D Mack, E Mui, R Estes… - International journal for …, 2002 - Elsevier
Survival of mice during the acute stage of Toxoplasmagondii infection was not influenced by
the MHC Class I gene, Ld, but was influenced by the MHC Class II genes, Ia and Ie. As …
the MHC Class I gene, Ld, but was influenced by the MHC Class II genes, Ia and Ie. As …
CD8+-T-Cell Response to Secreted and Nonsecreted Antigens Delivered by Recombinant Listeria monocytogenes during Secondary Infection
AR Tvinnereim, SE Hamilton, JT Harty - Infection and immunity, 2002 - Am Soc Microbiol
Understanding how existing antivector immunity impacts live vaccine delivery systems is
critical when the same vector system may be used to deliver different antigens. We …
critical when the same vector system may be used to deliver different antigens. We …
Structural basis of immunogenicity
S Stevanović - Transplant immunology, 2002 - Elsevier
The most important 'on–off'switch within the immune system are the T cells: these decide
whether an immune response has to be induced and maintained or not. Since T cells glean …
whether an immune response has to be induced and maintained or not. Since T cells glean …