Production and purification of a recombinant staphylococcal enterotoxin B vaccine candidate expressed in Escherichia coli
JD Coffman, J Zhu, JM Roach, S Bavari… - Protein expression and …, 2002 - Elsevier
An attenuated, recombinant form of Staphylococcus enterotoxin B (rSEB) was
overexpressed in Escherichia coli under transcriptional control of the T7 promoter. The 28 …
overexpressed in Escherichia coli under transcriptional control of the T7 promoter. The 28 …
Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen–DQ8 and human CD4 receptors: implications for …
BC Welcher, JH Carra, L DaSilva… - The Journal of …, 2002 - academic.oup.com
Streptococcal and staphylococcal infections result in significant human morbidity and
mortality. This study used a transgenic murine model expressing human major …
mortality. This study used a transgenic murine model expressing human major …
Immune protection against staphylococcal enterotoxin-induced toxic shock by vaccination with a Venezuelan equine encephalitis virus replicon
JS Lee, BK Dyas, SS Nystrom, CM Lind… - The Journal of …, 2002 - academic.oup.com
A candidate vaccine against staphylococcal enterotoxin B (SEB) was developed using a
Venezuelan equine encephalitis (VEE) virus vector. This vaccine is composed of a self …
Venezuelan equine encephalitis (VEE) virus vector. This vaccine is composed of a self …
Bacterial superantigen vaccines
RG Ulrich, MA Olson, S Bavari - US Patent 6,399,332, 2002 - Google Patents
The present invention relates to genetically attenuated superantigen toxin vaccines altered
such that superantigen attributes are absent, however the superantigen is effectively …
such that superantigen attributes are absent, however the superantigen is effectively …
Structural basis for abrogated binding between staphylococcal enterotoxin A superantigen vaccine and MHC‐IIα
HI Krupka, BW Segelke, RG Ulrich, S Ringhofer… - Protein …, 2002 - Wiley Online Library
Staphylococcal enterotoxins (SEs) are superantigenic protein toxins responsible for a
number of life‐threatening diseases. The X‐ray structure of a staphylococcal enterotoxin A …
number of life‐threatening diseases. The X‐ray structure of a staphylococcal enterotoxin A …