Mutations in the connexin26 (GJB2) gene account for about half of inherited non-syndromic
deafness cases in Western countries. The connexin26 protein is a subunit of gap junctions …

Gap junctional communication is a widespread mechanism for metabolic coupling of
adjoining cells. In the immune system, evidence has built up showing that lymphocytes …

In addition to neuronal synapses (chemical or electrical), gap junctions constitute a second
type of cell communication system. Gap junctions are structures that facilitate the …

The role of cytoskeletal elements in gap junction (GJ) assembly has been studied using
Novikoff hepatoma cells treated with cytochalasin B (CB) to disrupt actin filaments or with …

Gap-junction channels provide a widespread intercellular signalling mechanism. They are
constructed of a family of connexin membrane proteins that thread across the membrane …

Gap junctions, composed of connexins, provide a pathway of direct intercellular
communication for the diffusion of small molecules between cells. Evidence suggests that …

CD45 is a receptor protein-tyrosine phosphatase essential for T cell development and
lymphocyte activation. It is highly glycosylated, with multiple isoforms and glycoforms …

Gap junction intercellular communication channels permit the exchange of small regulatory
molecules and ions between neighbouring cells and coordinate cellular activity in diverse …

The Connexin (Cx) gene family acts as a tumor suppressor. However, it is unclear whether
the tumor-suppressing activity acquired by Cx gene transfection is mainly due to the …

Visualisation and monitoring of protein localisation and function using Green Fluorescent
Protein (GFP) tagged proteins is a well-established approach. We have sought to develop …