Pulmonary alveolar proteinosis: progress in the first 44 years

JF Seymour, JJ Presneill - … journal of respiratory and critical care …, 2002 - atsjournals.org
Pulmonary alveolar proteinosis is a rare clinical syndrome that was first described in 1958.
Subsequently, over 240 case reports and small series have described at least 410 cases in …

Hydrophobic surfactant proteins in lung function and disease

JA Whitsett, TE Weaver - New England Journal of Medicine, 2002 - Mass Medical Soc
Pulmonary surfactants consist of phospholipids and the hydrophobic proteins surfactant
protein B and surfactant protein C. These surfactants keep the alveoli in the lung open to the …

Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred

AQ Thomas, K Lane, J Phillips III, M Prince… - American journal of …, 2002 - atsjournals.org
Familial pulmonary fibrosis is a heterogeneous group of interstitial lung diseases of
unknown cause that is associated with multiple pathologic subsets. Mutations in the …

Mutations in the surfactant protein C gene associated with interstitial lung disease

LM Nogee, AE Dunbar, S Wert, F Askin, A Hamvas… - Chest, 2002 - journal.chestnet.org
34 Rybicki BA, Maliarik MJ, Malvitz E, et al. The influence of T cell receptor and cytokine
genes on sarcoidosis susceptibility in African Americans. Hum Immunol 1999; 60: 867–874 …

Pulmonary interstitial glycogenosis: a new variant of neonatal interstitial lung disease

AM Canakis, E Cutz, D Manson… - American journal of …, 2002 - atsjournals.org
We present the clinical, radiologic, and pathologic findings in lung biopsies from seven
infants with atypical neonatal lung disease. All seven infants presented with tachypnea …

[PDF][PDF] Molecular mechanisms of pulmonary fibrosis

A Pardo, M Selman - Front Biosci, 2002 - article.imrpress.com
Introduction 3. Lessons from the inflammatory pathway 3.1. The paradigm of type 1 or type 2
cytokine network commitment 3.2. Chemokines 3.2. 1. Chemokines in inflammatory/fibrotic …

Pediatric interstitial lung disease: children are not small adults

LL Fan, C Langston - American journal of respiratory and critical …, 2002 - atsjournals.org
Ichikado K, Honda O, Mihara N, Kozuka T, et al. Acute respiratory distress syndrome and
acute interstitial pneumonia: comparison of thin-section CT findings. J Comput Assist …

Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes

F Brasch, A Ten Brinke, G Johnen, M Ochs… - American journal of …, 2002 - atsjournals.org
Surfactant protein C (SP-C) is synthesized by type II pneumocytes as a 21-kD propeptide
(proSP-C) which is proteolytically processed to a 4.2-kD dipalmitoylated protein. To …

Lung surfactant in subacute pulmonary disease

G Devendra, RG Spragg - Respiratory research, 2002 - Springer
Pulmonary surfactant is a surface active material composed of both lipids and proteins that is
produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung …

Component-specific surface and physiological activity in bovine-derived lung surfactants

RH Notter, Z Wang, EA Egan, BA Holm - Chemistry and Physics of Lipids, 2002 - Elsevier
Composition, surface activity and effects on pressure–volume (P–V) mechanics are
examined for lavaged calf lung surfactant (LS) and the clinical exogenous surfactants …