Acromegaly: evidence for a direct relation between disease activity and cardiac dysfunction in patients without ventricular hypertrophy
BL Herrmann, C Bruch, B Saller, T Bartel… - Clinical …, 2002 - Wiley Online Library
Summary background and aims Cardiac abnormalities, such as cardiomegaly and
congestive heart failure, occur frequently in advanced acromegaly. Abnormalities of systolic …
congestive heart failure, occur frequently in advanced acromegaly. Abnormalities of systolic …
PLC-γ1 is required for IGF-I protection from cell death induced by loss of extracellular matrix adhesion
A Chattopadhyay, G Carpenter - Journal of Cell Science, 2002 - journals.biologists.com
Phospholipase C-γ1, a tyrosine kinase substrate, hydrolyses phosphatidylinositol 4, 5-
bisphosphate to produce inositol 1, 4, 5-trisphosphate and diacylglycerol, which act as …
bisphosphate to produce inositol 1, 4, 5-trisphosphate and diacylglycerol, which act as …
Differential effects of des IGF-1 on Erks, AKT-1 and P70 S6K activation in mouse skeletal and cardiac muscle
M Li, C Li, WS Parkhouse - Molecular and cellular biochemistry, 2002 - Springer
Alterations in the degree of the phosphorylation of ERK1/2, Akt-1 and p70 S6K in mouse
skeletal and cardiac muscle was examined in vivo following an intraperitoneal injection of …
skeletal and cardiac muscle was examined in vivo following an intraperitoneal injection of …
[图书][B] Function of the SH2 domain-containing protein tyrosine phosphatase, SHP-2, in myogenesis
MI Kontaridis - 2002 - search.proquest.com
Myogenesis involves expression of muscle-specific genes, cell-cell recognition and
multinucleation. Growth factor specific responses are thought to differentially regulate these …
multinucleation. Growth factor specific responses are thought to differentially regulate these …
[图书][B] The sodium (+)/potassium (+)-ATPase as a signal transducer
MS Haas - 2002 - search.proquest.com
Binding of ouabain to the Na+/K+-ATPase activates tyrosine phosphorylation of the EGFR,
Src, and MAPK in both cardiac myocytes and A7r5 cells. We explored the roles of Src and …
Src, and MAPK in both cardiac myocytes and A7r5 cells. We explored the roles of Src and …
[图书][B] Stimulation of the mitogen-activated protein kinase (MAPK) pathway in DDT1MF-2 cells by adenosine A1 receptors and histamine H1 receptors
AJ Robinson - 2002 - search.proquest.com
The mitogen-activated protein kinases (MAPKs) are a group of serine/threonine protein
kinases comprising of three main subfamilies. Extracellular signal-regulated kinases (ERKs …
kinases comprising of three main subfamilies. Extracellular signal-regulated kinases (ERKs …