Tumor suppressor genes in normal and malignant hematopoiesis
U Krug, A Ganser, HP Koeffler - Oncogene, 2002 - nature.com
Over the last decade, a growing number of tumor suppressor genes have been discovered
to play a role in tumorigenesis. Mutations of p53 have been found in hematological …
to play a role in tumorigenesis. Mutations of p53 have been found in hematological …
Effect of flavonoids on cell cycle progression in prostate cancer cells
T Kobayashi, T Nakata, T Kuzumaki - Cancer letters, 2002 - Elsevier
The effect of some flavonoids, which are components of fruits, vegetables, and peas, on the
cell cycle progression of human LNCaP prostate cancer cells has been investigated in this …
cell cycle progression of human LNCaP prostate cancer cells has been investigated in this …
Maturation of fetal hepatocytes in vitro by extracellular matrices and oncostatin M: induction of tryptophan oxygenase
A Kamiya, N Kojima, T Kinoshita, Y Sakai, A Miyaijma - Hepatology, 2002 - Elsevier
Previously, we described that embryonic day 14.5 (E14. 5) mouse fetal hepatocytes
differentiate to express tyrosine amino transferase (TAT) and glucose-6-phosphatase, which …
differentiate to express tyrosine amino transferase (TAT) and glucose-6-phosphatase, which …
Activation of the Drosophila MLK by ceramide reveals TNF-α and ceramide as agonists of mammalian MLK3
Mixed lineage kinases (MLKs) are MAPKKK members that activate JNK and reportedly lead
to cell death. However, the agonist (s) that regulate MLK activity remain unknown. Here, we …
to cell death. However, the agonist (s) that regulate MLK activity remain unknown. Here, we …
IL-1β during in vitro decidualization in primate
Z Strakova, S Srisuparp, AT Fazleabas - Journal of reproductive …, 2002 - Elsevier
The sequence of biochemical and molecular events associated with decidualization in the
primate remain unclear. In the baboon, the sequential changes during this period in vivo are …
primate remain unclear. In the baboon, the sequential changes during this period in vivo are …
Downregulation of c-Jun expression by transcription factor C/EBPα is critical for granulocytic lineage commitment
J Rangatia, RK Vangala, N Treiber… - … and cellular biology, 2002 - Taylor & Francis
The transcription factor C/EBPα is crucial for the differentiation of granulocytes. Conditional
expression of C/EBPα triggers neutrophilic differentiation, and C/EBPα can block 12-O …
expression of C/EBPα triggers neutrophilic differentiation, and C/EBPα can block 12-O …
Morphological changes induced by extracellular matrix are correlated with maturation of rat small hepatocytes
S Sugimoto, T Mitaka, S Ikeda, K Harada… - Journal of cellular …, 2002 - Wiley Online Library
Small hepatocytes (SHs), which are known to be hepatic progenitor cells, were isolated from
an adult rat liver. SHs in a colony sometimes change their shape from small to large and …
an adult rat liver. SHs in a colony sometimes change their shape from small to large and …
Integrins α6Aβ1 and α6Bβ1 promote different stages of chondrogenic cell differentiation
D Segat, R Comai, E Di Marco, A Strangio… - Journal of Biological …, 2002 - ASBMB
The differentiation of chondrocytes and of several other cell types is associated with a switch
from the α 6B to the α 6A isoform of the laminin α 6 β 1 integrin receptor. To define whether …
from the α 6B to the α 6A isoform of the laminin α 6 β 1 integrin receptor. To define whether …
Type I collagen inhibits hydroxyl radical-induced apoptosis
Y He, J Chen, J Ren, G Wang… - The journal of …, 2002 - academic.oup.com
The extracellular matrix (ECM) plays an important role in cell differentiation and apoptosis.
Collagen is the major component of ECM. Here, an ESR signal of the hydroxyl radicals …
Collagen is the major component of ECM. Here, an ESR signal of the hydroxyl radicals …
Use of a non-mammalian DNA virus to express an exogenous gene in a mammalian cell
FM Boyce - US Patent 6,338,962, 2002 - Google Patents
Disclosed are methods, nucleic acids, and cells for expressing an exogenous gene in a
mammalian cell, involving introducing into the cell a non-mammalian DNA virus (eg, a …
mammalian cell, involving introducing into the cell a non-mammalian DNA virus (eg, a …