Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications

R Leclercq - Clinical infectious diseases, 2002 - academic.oup.com
Resistance to macrolides and lincosamides is increasingly reported in clinical isolates of
gram-positive bacteria. The multiplicity of mechanisms of resistance, which include …

What happened to the streptococci: overview of taxonomic and nomenclature changes

R Facklam - Clinical microbiology reviews, 2002 - Am Soc Microbiol
Since the division of the Streptococcus genus into enterococci, lactococci, and streptococci
in 1984, many changes in the nomenclature and taxonomy of the Streptococcus genus have …

Endodontic infections: concepts, paradigms, and perspectives

JF Siqueira Jr - Oral Surgery, Oral Medicine, Oral Pathology, Oral …, 2002 - Elsevier
Overwhelming evidence indicates that periradicular diseases are infectious disorders. The
question now is no longer whether microorganisms are involved in the pathogenesis of such …

Trends in antimicrobial prescribing rates for children and adolescents

LF McCaig, RE Besser, JM Hughes - Jama, 2002 - jamanetwork.com
ContextAnnual rates of antimicrobial prescribing for children by office-based physicians
increased from 1980 through 1992. The development of antimicrobial resistance, which …

Fluoroquinolone resistance among Gram-positive cocci

DC Hooper - The Lancet infectious diseases, 2002 - thelancet.com
Resistance to fluoroquinolones among Gram-positive cocci has emerged as these
antimicrobial agents have become extensively used in clinical medicine. Resistance is …

Antimicrobial resistance and aging: beginning of the end of the antibiotic era?

TT Yoshikawa - Journal of the American Geriatrics Society, 2002 - Wiley Online Library
Throughout the history of mankind, infectious diseases have remained a major cause of
death and disability. Although industrialized nations, such as the United States, have …

Changes in antibiotic prescribing for children after a community-wide campaign

JF Perz, AS Craig, CS Coffey, DM Jorgensen, E Mitchel… - Jama, 2002 - jamanetwork.com
ContextOveruse of antibiotics has contributed to microbial resistance, compromising the
treatment of bacterial infections. Very high levels (> 50%) of antibiotic resistance among …

Regional Trends in Antimicrobial Resistance among Clinical Isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United …

C Thornsberry, DF Sahm, LJ Kelly… - Clinical Infectious …, 2002 - academic.oup.com
Abstract The ongoing TRUST (Tracking Resistance in the United States Today) study, which
began monitoring antimicrobial resistance among respiratory pathogens in 1996, routinely …

Historical changes in pneumococcal serogroup distribution: implications for the era of pneumococcal conjugate vaccines

DR Feikin, KP Klugman - Clinical Infectious Diseases, 2002 - academic.oup.com
Of the 90 pneumococcal serotypes, the 7 in the licensed pneumococcal conjugate vaccine
(Prevnar) currently account for> 80% of invasive pneumococcal infections among children in …

The genes encoding virulence-associated proteins and the capsule of Streptococcus pneumoniae are upregulated and differentially expressed in vivo

AD Ogunniyi, P Giammarinaro, JC Paton - Microbiology, 2002 - microbiologyresearch.org
The polysaccharide capsule of Streptococcus pneumoniae and several well-characterized
virulence proteins are known to contribute to the pathogenesis of pneumococcal disease …