Chemokines and their receptors are involved in the pathogenesis of diseases ranging from
asthma to AIDS. Chemokine receptors are G-protein-coupled serpentine receptors that …

Chemokines are the largest family of cytokines in human immunophysiology. These proteins
are defined by four invariant cysteines and are categorized based on the sequence around …

The AIDS pandemic continues to spread unchecked in many parts of the world, with greater
than 34 million individuals currently infected with human immunodeficiency virus (HIV) …

Human immunodeficiency virus (HIV) exploits cell surface receptors to attach to and gain
entry into cells. The HIV envelope spike glycoprotein on the surface of virus particles binds …

Viruses have evolved mechanisms to avoid the host immune system, including means of
escaping detection by both the innate and adaptive immune responses. Natural killer (NK) …

Chemokine receptor CXCR4 plays an important role in the immune system and the cellular
entry of human immunodeficiency virus type 1 (HIV-1). To probe the stereospecificity of the …

Chemokines are small cytokines that control a wide variety of biological and pathological
processes, from immunosurveillance to inflammation, and from viral infection to cancer. The …

Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is the eighth and most recently
identified human herpesvirus (HHV-8). KSHV was discovered in 1994 by Chang et al. who …

DNA immunizations with glycoprotein 120 (gp120) of human immunodeficiency virus–1 (HIV-
1) usually require boosting with protein or viral vaccines to achieve optimal efficacy. Here …

The M3 protein encoded by murine γherpesvirus68 (γHV68) functions as an immune system
saboteur by the engagement of chemoattractant cytokines, thereby altering host antiviral …