Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype
YX Pan, E Bolan, GW Pasternak - Biochemical and biophysical research …, 2002 - Elsevier
Although orphanin FQ/nociceptin (OFQ/N) receptors are a member of the opioid receptor
family of receptors, they bind traditional opioids with very poor affinity. We now demonstrate …
family of receptors, they bind traditional opioids with very poor affinity. We now demonstrate …
Involvement of the neuropeptide nociceptin/orphanin FQ in kainate seizures
G Bregola, S Zucchini, D Rodi, A Binaschi… - Journal of …, 2002 - Soc Neuroscience
The neuropeptide nociceptin/orphanin FQ (N/OFQ) has been shown to modulate neuronal
excitability and neurotransmitter release. Previous studies indicate that the mRNA levels for …
excitability and neurotransmitter release. Previous studies indicate that the mRNA levels for …
Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: an in vitro and in vivo study
C Sakurada, S Sakurada, T Orito, K Tan-No… - Biochemical …, 2002 - Elsevier
We analyzed spinal metabolic pathway of nociceptin/orphanin FQ related to pain-
transmission or modulation in the both in vitro and in vivo experiments. Nociceptin was …
transmission or modulation in the both in vitro and in vivo experiments. Nociceptin was …