The conserved process of TCR/CD3 complex down-modulation by SIV Nef is mediated by the central core, not endocytic motifs

TM Schaefer, I Bell, ME Pfeifer, M Ghosh, RP Trible… - Virology, 2002 - Elsevier
The Nef protein of Simian immunodeficiency virus (SIV) associates with multiple T
lymphocyte signaling proteins, including the T cell receptor (TCR) ζ chain. We demonstrate …

In Vitro Production and Characterization of Partly Assembled Human CD3 Complexes

J Kastrup, LØ Pedersen, J Dietrich… - Scandinavian …, 2002 - Wiley Online Library
Pairwise assembly of human CD3 chains takes place in the endoplasmic reticulum of T
cells. Subsequently, the CD3 heterodimers form complexes with Tiα and Tiß chains forming …