Determination of moxifloxacin in human plasma by liquid chromatography electrospray ionization tandem mass spectrometry

K Vishwanathan, MG Bartlett, JT Stewart - Journal of pharmaceutical and …, 2002 - Elsevier
Moxifloxacin is an advanced-generation, 8-methoxy fluoroquinolone that is active against a
broad spectrum of pathogens, including antibiotic resistant Streptococcus pneumoniae …

A prospective, multicentre study of moxifloxacin concentrations in the sinus mucosa tissue of patients undergoing elective surgery of the sinus

P Gehanno, S Darantiere, C Dubreuil… - Journal of …, 2002 - academic.oup.com
A pharmacokinetic study was carried out to determine moxifloxacin concentrations in sinus
tissue, after oral moxifloxacin 400 mg once daily for 5 days to patients with chronic sinusitis …

Pharmacodynamics of 750 mg and 500 mg doses of levofloxacin against ciprofloxacin-resistant strains of Streptococcus pneumoniae

PD Lister - Diagnostic microbiology and infectious disease, 2002 - Elsevier
An in vitro pharmacokinetic model (IVPM) was used to evaluate the pharmacodynamics of
the 750 mg and 500 mg doses of levofloxacin against 4 ciprofloxacin-nonsusceptible …

Pharmacodynamics of Gatifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model: Impact of Area under the Curve/MIC Ratios on …

PD Lister - Antimicrobial agents and chemotherapy, 2002 - Am Soc Microbiol
Previous studies have demonstrated that fluoroquinolone area under the curve (AUC)/MIC
ratios of 30 to 50 are sufficient to eradicate pneumococci from in vitro pharmacokinetic …

A study on the toxicity of intravitreal levofloxacin in rabbits

B Gurler, Y Ozkul, M Bitiren, S Karadede… - Current eye …, 2002 - Taylor & Francis
Purpose. To investigate the retinal toxicity of different doses of intravitreal injections of
levofloxacin in a rabbit model, which is the levorotatory component of ofloxacin and …

Moxifloxacin sensitivity of respiratory pathogens in the United Kingdom

T Dorai-John, CJ Thomson, SGB Amyes - Journal of chemotherapy, 2002 - Taylor & Francis
The in vitro activity of moxifloxacin and comparator agents against respiratory isolates from a
range of geographically distinct centres around the United Kingdom was investigated in the …

Moraxella (Branhamella) catarrhalis

D Zoutman - Community-Acquired Pneumonia, 2002 - Springer
oxidase-positive, nonmotile gram-negative diplococcus. It was initially named Neisseria
catarrhalis until Catlin (1970) demonstrated that this organism was distinct from the …