Cell surface receptors, virus entry and tropism of primate lentiviruses

PR Clapham, Á McKnight - Journal of General Virology, 2002 - microbiologyresearch.org
Human immunodeficiency virus (HIV) exploits cell surface receptors to attach to and gain
entry into cells. The HIV envelope spike glycoprotein on the surface of virus particles binds …

CCR5 and HIV infection

C Blanpain, F Libert, G Vassart… - Receptors and …, 2002 - Taylor & Francis
Chemokines and chemokine receptors play a crucial role in the trafficking of leukocyte
populations across the body, and are involved in the development of a large variety of …

CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor

K Vermeire, Y Zhang, K Princen, S Hatse, MF Samala… - Virology, 2002 - Elsevier
The novel antiviral agent cyclotriazadisulfonamide (CADA) inhibited human
immunodeficiency virus (HIV)(IC50, 0.3–3.2 μM) and human herpesvirus 7 (HHV-7) infection …

HIV receptors and cellular tropism

RA Weiss - IUBMB life, 2002 - Wiley Online Library
Viruses use specific cell surface receptors to bind to and subsequently gain entry into their
host cells. Some retroviruses such as HIV‐1 and HIV‐2 utilize one receptor for high‐affinity …

Method for preventing HIV-1 infection of CD4+ cells

GP Allaway, VM Litwin, PJ Maddon… - US Patent 6,344,545, 2002 - Google Patents
HIV-1 to CD4" cells which comprise contacting CD" cells with a non-chemokine agent
capable of binding to a chemokine receptor in an amount and under conditions Such that …

Structure, function and modulation of chemokine receptors: members of the g-protein-coupled receptor superfamily

Z Huang - Mini Reviews in Medicinal Chemistry, 2002 - ingentaconnect.com
Chemokine receptors are membrane proteins that play an important role in inflammation
and the cellular entry of human immunodeficiency virus type I (HIV-1). Understanding the …

Synthetic peptides for study of human immunodeficiency virus infection

M Dettin, C Scarinci, A Pasquato, C Di Bello - Applied biochemistry and …, 2002 - Springer
The formation of a complex among gp120, CD4, and CCR5/CXCR4 represents a key step in
human immunodeficiency virus (HIV) infection. The use of synthetic peptides reproducing …

Lipids in viral fusion

A Puri, M Paternostre, R Blumenthal - Liposome Methods and Protocols, 2002 - Springer
Enveloped animal viruses infect host cells by fusion of viral and target membranes. This
crucial fusion event occurs either with the plasma membrane of the host cells or with the …

[图书][B] HIV membrane fusion: Analysis of novel inhibitors

TT Strassmaier - 2002 - search.proquest.com
A reporter-gene cell-cell fusion assay was developed and used to study inhibition of HIV-
mediated membrane fusion. The cell-cell fusion assay is simple, highly sensitive, and …

Phänotypische Charakterisierung des viralen Hüllproteins (Env) von HIV-1 durch Konstruktion rekombinanter HIV-1-Varianten

S Reinberger - 2002 - ediss.sub.uni-hamburg.de
Das humane Immundefizienzvirus HIV-1 zeichnet sich durch eine hohe Variabilität zwischen
den Virusisolaten aus verschiedenen Patienten aus, aber auch durch die Fähigkeit, sich …