Recent evidence enriches our understanding of the molecular sites of action of cocaine
reward and locomotor stimulation. Dopamine transporter blockade by cocaine appears a …

The dopamine transporter is elevated in adults with attention deficit hyperactivity disorder
(ADHD) compared with healthy controls [Lancet 354 (1999) 2132]. The findings have been …

Genetic association studies provide considerable evidence that the 10‐repeat allele of a
variable number tandem repeat (VNTR) in the 3′‐untranslated region (3′‐UTR) of the …

Posttraumatic stress disorder (PTSD) is a chronic anxiety disorder that follows exposure to
extreme events. A large twin study of Vietnam veterans had demonstrated a significant …

Converging evidence has implicated abnormalities of dopamine neurotransmission to the
pathology of attention deficit hyperactivity disorder (ADHD). Several genetic association …

Dopamine transporter (DAT) levels vary in normal subjects and deviate from the normal
range in pathological states. We investigated mechanisms by which the DAT gene may …

The norepinephrine, dopamine and serotonin transporters (NET, DAT and SERT,
respectively), limit cellular signaling by recapturing released neurotransmitter, and serve as …

Early childhood externalizing behavior is a stable and heritable pattern of aggressive and
delinquent behavior that often leads to the development of serious psychiatric disorders …

Cigarette smoking, like many addictive behaviors, has been shown to have a genetic
component. The dopamine transporter (DAT) gene (SLC6A3) encodes a protein that …

To advance the science of tobacco control, an enhanced understanding of the bio-
behavioral basis of nicotine addiction is needed. In this study, we provide an overview of …