On the importance of being co-transcriptional

KM Neugebauer - Journal of cell science, 2002 - journals.biologists.com
Intense research in recent years has shown that many pre-mRNA processing events are co-
transcriptional or at least begin during RNA synthesis by RNA polymerase II (Pol II). But is it …

[HTML][HTML] The mRNA export factor Dbp5 is associated with Balbiani ring mRNP from gene to cytoplasm

J Zhao, SB Jin, B Björkroth, L Wieslander… - The EMBO …, 2002 - embopress.org
The DEAD box RNA helicase Dbp5 is essential for nucleocytoplasmic transport of mRNA–
protein (mRNP) complexes. Dbp5 is present mainly in the cytoplasm and is enriched at the …

HEL/UAP56 binds cotranscriptionally to the Balbiani ring pre-mRNA in an intron-independent manner and accompanies the BR mRNP to the nuclear pore

E Kiesler, F Miralles, N Visa - Current Biology, 2002 - cell.com
The splicing factor UAP56/HEL/Sub2p is essential for mRNA export [1-4]. It has been
proposed [1, 2] that UAP56/HEL/Sub2p interacts with the pre-mRNA during splicing and …

Nuclear export of messenger RNA

E Izaurralde - Nuclear transport, 2002 - Springer
Messenger RNAs (mRNAs) exist in the cell in dynamic association with multiple distinct
proteins. The mRNA export cargo is therefore a ribonucleoprotein particle (mRNP). The most …

A novel conserved RNA-binding domain protein, RBD-1, is essential for ribosome biogenesis

P Bjork, G Baurén, SB Jin, YG Tong… - Molecular biology of …, 2002 - Am Soc Cell Biol
Synthesis of the ribosomal subunits from pre-rRNA requires a large number of trans-acting
proteins and small nucleolar ribonucleoprotein particles to execute base modifications, RNA …

[图书][B] The splicing of U12-type introns is a rate-limiting step in gene expression

AA Patel - 2002 - search.proquest.com
Metazoan genes have recently been found to contain a novel class of introns that display
non-canonical consensus sequences and are excised by a distinct splicing machinery …

Method for localizing and identifying epitopes

U Skoglund, N Visa - 2002 - Google Patents
The present invention relates to a method for localizing and identifying specific epitopes on
a molecule. The molecule of interest can be localized in a cell or in a test tube. The invention …