Telomerase is a ribonucleoprotein complex that catalyses the addition of TTAGGG repeats
onto telomeres, repetitive DNA structures found at the ends of linear chromosomes. The …

The nucleolus represents a highly dynamic nuclear compartment of the interphase nucleus.
It plays a key role in ribosome biogenesis. The number of nucleoli, their size, and their …

The limited capacity to divide is one of the major differences between normal somatic cells
and cancerous cells. This 'finite life span'of somatic cells is closely linked to loss of telomeric …

Human telomerase, a cellular reverse transcriptase specifically activated in most malignant
tumors and usually inactive in normal somatic cells, plays an important role in …

Aim: The study was designed to explore the effects of antisense human telomerase RNA
(ahTR) on the malignant phenotype of gastric carcinoma cell line SGC‐7901, and its …

Maintenance of telomere length is crucial for survival of cells. Telo-merase, an enzyme that
is responsible for elongation of shortened telomeres, is active in human germ cells as well …

Background: To explore the possible regulatory mechanisms of telomerase, we examined
the telomerase activity (TA), expression of human telomerase RNA (hTR), human …

The past decade has witnessed an explosion of knowledge concerning the structure and
function of chromosome terminal structures—telomeres. Today's telomere research has …

In this report, we studied the relationship between telomerase activity and in vitro
differentiation of osteosarcoma cells. Human osteosarcoma cells (HOS-8603) were treated …