Since RGD peptides (R: arginine; G: glycine; D: aspartic acid) have been found to promote
cell adhesion in 1984 (Cell attachment activity of fibronectin can be duplicated by small …

Integrins are a family of cell adhesion receptors that support and modulate a variety of
cellular functions that are required for tumor metastasis. Integrins expressed by tumor cells …

Expression of adhesion receptor integrin αvβ3 in an activated functional form strongly
promotes metastasis in human breast cancer cells. Here, we report that αvβ3 cooperates …

Purpose: The manner in which surface roughness of implants affects bone-implant
integration remains unknown. This study correlated morphologic profiles of bone-implant …

The molecular mechanism leading to the cancer metastasis to bone is poorly understood but
yet determines prognosis and therapy. Here, we define a new molecular pathway that may …

Focal adhesion kinase (FAK) and hypoxia‐inducible factor (HIF‐1α) are both up‐regulated
in glioblastoma multiforme (GBMs), particularly in invasive zones. Because FAK may play an …

Osteogenic cells express some matrix proteins at early culture intervals. The aim of this
study was to determine if, and in what proportion, cells used for plating contain bone …

Recent evidence demonstrates that interactions between different integrins that are present
on the cell surface can strongly influence the adhesive function of individual receptors. In …

The present study investigated whether osteoblasts could attach to a culture substratum
through a surface texture-dependent mechanism. Four test groups were used:(A) …

Bone sialoprotein (BSP) is a member of the SIBLINGS family, normally restricted to the
skeleton, but it has been shown to be ectopically expressed in some human invasive …