The neurobiology and control of anxious states

MJ Millan - Progress in neurobiology, 2003 - Elsevier
Fear is an adaptive component of the acute “stress” response to potentially-dangerous
(external and internal) stimuli which threaten to perturb homeostasis. However, when …

The Vogel conflict test: procedural aspects, γ-aminobutyric acid, glutamate and monoamines

MJ Millan, M Brocco - European journal of pharmacology, 2003 - Elsevier
A multitude of mechanisms are involved in the control of emotion and in the response to
stress. These incorporate mediators/targets as diverse as γ-aminobutyric acid (GABA) …

Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex

J González-Maeso, T Yuen, BJ Ebersole… - Journal of …, 2003 - Soc Neuroscience
Most neuropharmacological agents and many drugs of abuse modulate the activity of
heptahelical G-protein-coupled receptors. Although the effects of these ligands result from …

The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism

GA Higgins, M Enderlin, M Haman, PJ Fletcher - Psychopharmacology, 2003 - Springer
In the present series of studies, we have investigated the effects of antagonists selective for
the 5-HT 2A, 5-HT 2B and 5-HT 2C receptors on motor and'impulsive'-type behaviours …

Focused microarray analysis

E Wurmbach, T Yuen, SC Sealfon - Methods, 2003 - Elsevier
We describe detailed protocols and results with an integrated platform for studying relative
transcript expression, including microarray design and fabrication, analysis and calibration …

Fenfluramine evokes 5‐HT2A receptor‐mediated responses but does not displace [11C]MDL 100907: Small animal PET and gene expression studies

E Hirani, T Sharp, M Sprakes, P Grasby, S Hume - Synapse, 2003 - Wiley Online Library
The in vivo binding of the 5‐HT2A receptor‐selective positron emission tomography (PET)
ligand [11C] MDL 100907 and its sensitivity to endogenous 5‐HT were quantified in rat brain …

Effects of autoshaping procedures on 3H-8-OH-DPAT-labeled 5-HT1a binding and 125I-LSD-labeled 5-HT2a binding in rat brain

A Tomie, J Di Poce, A Aguado, A Janes, D Benjamin… - Brain research, 2003 - Elsevier
Effects of experience with Pavlovian autoshaping procedures on lever-press autoshaping
conditioned response (CR) performance and 3H-8-OH-DPAT-labeled binding of 5-HT1a …

LSD y alucinógenos

JS Puig - Adicciones, 2003 - adicciones.es
Objetivo: realizar una revisión del LSD y otros alucinógenos desde un punto de vista
histórico-cultural, farmacológico y de consecuencias clínicas, especialmente psiquiátricas …

Differential regulation of rat peripheral 5-HT2A and 5-HT2B receptor systems: influence of drug treatment

MJ Enguix, L Sanchez, M Villazon, J Brea… - Naunyn-Schmiedeberg's …, 2003 - Springer
Most studies of 5-HT 2 receptor regulation have been carried out on the central nervous
system (CNS)(which expresses 5-HT 2A and 5-HT 2C receptors); very few in vitro studies …

Repeated administration of the novel antipsychotic olanzapine does not modulate NMDA-sensitive glutamate and 5HT2 serotonin receptors in rats

O Gandolfi, M Voltattorni, R Gaggi… - … Schmiedeberg's archives of …, 2003 - Springer
Antipsychotic drugs reportedly show a common property in facilitating glutamatergic
transmission in rat cerebral cortex. Since the binding of the radiolabelled channel blocker [3 …