During the past decade, proof of the principle that peptide receptors can be used
successfully for in vivo targeting of human cancers has been provided. The molecular basis …

Melatonin, the major hormone produced by the pineal gland, displays characteristic daily
and seasonal patterns of secretion. These robust and predictable rhythms in circulating …

Fear is an adaptive component of the acute “stress” response to potentially-dangerous
(external and internal) stimuli which threaten to perturb homeostasis. However, when …

Peptide hormones within the secretin-glucagon family are expressed in endocrine cells of
the pancreas and gastrointestinal epithelium and in specialized neurons in the brain, and …

Neurohormones similar to those of mammals are carried in fish by hypothalamic nerve fibers
to regulate directly follicle-stimulating hormone (FSH) and luteinizing hormone (LH) …

Recent findings have shed new light on the role of peripheral nerves in the skin and
established a modern concept of cutaneous neurobiology. Closely related monodirectional …

Dipeptidyl peptidase IV (DP-IV) is a cell surface serine dipeptidase that is involved in the
regulation of the incretin hormones, glucagon-like peptide (GLP-1) and glucose-dependent …

Susceptibility to drug addiction depends on genetic and environmental factors and their
complex interactions. Studies with mammalian models have identified molecular targets …

We recently identified a novel mechanism for modulation of the phosphorylation state and
function of theN-methyl-d-aspartate (NMDA) receptor via the scaffolding protein RACK1. We …

The pituitary adenylate cyclase‐activating polypeptide (PACAP) is a neuropeptide
belonging to the VIP/secretin/glucagon family of peptides, produced by the lymphoid cells …