▪ Abstract Stem cell biology is scientifically, clinically, and politically a current topic. The
hematopoietic stem cell, the common ancestor of all types of blood cells, is one of the best …

The discovery and development of the bicyclam AMD3100—a chemokine receptor
antagonist—has highlighted the therapeutic potential of such compounds in HIV infection …

Background Myocardial regeneration via stem-cell mobilisation at the time of myocardial
infarction is known to occur, although the mechanism for stem-cell homing to infarcted tissue …

Hematopoietic progenitor cells (HPCs) normally reside in the bone marrow (BM) but can be
mobilized into the peripheral blood (PB) after treatment with GCSF or chemotherapy. In …

Hematopoietic stem cells rarely contribute to hepatic regeneration, however, the
mechanisms governing their homing to the liver, which is a crucial first step, are poorly …

In the maternal decidua, natural killer (NK) cells, characterized by lack of CD16, are found in
direct contact with the fetal extravillous trophoblasts (EVTs). It is yet unknown which factors …

The chemotactic factors directing interneuron migration during cerebrocortical development
are essentially unknown. Here we identify the CXC chemokine receptor 4 (CXCR4) in …

Chemokines are small proteins that act as cell attractants via the activation of G protein-
coupled receptors. Chemokines play an important role in several pathophysiological …

Directed cellular migrations underlie immune system organization. Chemokines and their
receptors (along with surface‐adhesion molecules) are central to these migrations, targeting …

Primordial germ cells follow a characteristic developmental path that is manifested in the
specialized regulation of basic cell functions and behaviour. Recent studies in zebrafish …