Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of …

Inferior vena caval filters can be inserted percutaneously to prevent PE, but they do not halt
the thrombotic process. They also serve as a nidus for recurrent venous thromboembolism …

Background: Clinicians should consider the clinical impact of anticoagulant-related bleeding
when deciding on the duration of anticoagulant therapy in patients with venous …

Background Warfarin is very effective in preventing recurrent venous thromboembolism but
is also associated with a substantial risk of bleeding. After three months of conventional …

Background For many patients with venous thromboembolism, secondary prevention with
vitamin K antagonists is not extended beyond six months, since the risk of recurrence may …

Background—We have shown that normal D-dimer levels obtained after the discontinuation
of oral anticoagulant treatment (OAT) has a high negative predictive value for recurrent …

Background: The optimal means of achieving therapeutic oral anticoagulation in the
outpatient setting has not been determined. Objective: To compare a 10-mg dosing …

Background In a previous study of the prevention of venous thromboembolism after total
knee replacement, the efficacy of ximelagatran, an oral direct thrombin inhibitor that does not …

Objectives: We sought to determine the prevalence of pulmonary artery thrombosis in
patients with Eisenmenger syndrome and to identify individuals at highest risk. Background …

Hematologists are increasingly involved in the diagnosis and management of patients with
venous and arterial thromboembolic disorders. There have been major advances in recent …