Heat shock proteins and aging in Drosophila melanogaster
G Morrow, RM Tanguay - Seminars in cell & developmental biology, 2003 - Elsevier
Heat shock proteins (Hsps) are conserved molecular chaperones that are upregulated
following exposure to environmental stress and during aging. The mechanisms underlying …
following exposure to environmental stress and during aging. The mechanisms underlying …
Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress
MJ Hercus, V Loeschcke, SIS Rattan - Biogerontology, 2003 - Springer
We assessed the impact of repeated episodes of a mild heat stress on lifespan, fecundity,
heat stress resistance and Hsp70 expression in Drosophila melanogaster. There was a …
heat stress resistance and Hsp70 expression in Drosophila melanogaster. There was a …
Hormesis in aging and longevity
N Minois, SIS Rattan - Modulating aging and longevity, 2003 - books.google.com
The possibility of gerontomodulation through hormesis is rooted in the idea of making use of
the fundamental characteristic of living systems, that is, the ability of self-maintenance and …
the fundamental characteristic of living systems, that is, the ability of self-maintenance and …
Delaying aging: could the study of hormesis be more helpful than that of the genetic pathway used to survive starvation?
E Le Bourg - Biogerontology, 2003 - Springer
Many studies have described the positive effect of food restriction on aging and longevity in
rodents as well as a genetic pathway activated in response to starvation in nematodes and …
rodents as well as a genetic pathway activated in response to starvation in nematodes and …
Energy, stress and the invalid linear no-threshold premise: a generalization illustrated by ionizing radiation
PA Parsons - Biogerontology, 2003 - Springer
The linear no-threshold (LNT) premise for environmental agents is assessed in the context
of the habitats of organisms where exposure to a multiplicity of environmental agents occurs …
of the habitats of organisms where exposure to a multiplicity of environmental agents occurs …
Molecular chaperones and cellular aging
G Morrow, RM Tanguay - Aging of Cells in and Outside the Body, 2003 - Springer
Chaperones are phylogeneticaliy conserved proteins involved in the proper folding of
nascent proteins and repair of damaged or misfolded proteins. They are ubiquitously …
nascent proteins and repair of damaged or misfolded proteins. They are ubiquitously …