[图书][B] Drug delivery systems

VV Ranade, MA Hollinger, JB Cannon - 2003 - taylorfrancis.com
Drug delivery technologies represent a vast and vital area of Research and Development.
The demand for innovative drug delivery systems continues to grow, and this growth …

In Vitro System to Evaluate Oral Absorption of Poorly Water-Soluble Drugs: Simultaneous Analysis on Dissolution and Permeation of Drugs

M Kataoka, Y Masaoka, Y Yamazaki, T Sakane… - Pharmaceutical …, 2003 - Springer
Purpose. The aim of the present work was to develop a new in vitro system to evaluate oral
absorption of poorly water-soluble drugs by utilizing Caco-2 monolayers. Methods. Caco-2 …

Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co …

J Hu, KP Johnston, RO Williams III - European Journal of Pharmaceutical …, 2003 - Elsevier
A spray freezing into liquid (SFL) particle engineering technology has been developed to
produce micronized powders to enhance the dissolution of poorly water soluble active …

Physicochemical characterization and principles of oral dosage form selection

GE Amidon, X He, MJ Hageman - Burger's medicinal chemistry …, 2003 - Wiley Online Library
Identifying an active lead molecule, selecting a viable drug candidate, and developing a
marketable product are profoundly influenced by molecular properties and dosage form …

[图书][B] A nanoparticle engineering process: Spray-freezing into liquid to enhance the dissolution of poorly water soluble drugs

J Hu - 2003 - search.proquest.com
It is estimated that about 40% of compounds being developed by the pharmaceutical
industry are poorly water soluble. A limiting factor in the oral bioavailability of poorly water …

[PDF][PDF] Understanding the solid forms of 5-Ephenylethenylbenzofuroxan with different in vivo anti-T. cruzi. activity

SB Honorato, W Porcal, A Merlino, J Ellena… - Rev Virtual …, 2003 - academia.edu
Abstract 5E-Phenylethenylbenzofuroxan (5PhEBfx) was reported as an excellent anti-
Chagas drug candidate. However, its oral bioavailability was affected by the crystallization …

Physicochemical Characterization and Oral Dosage Form Selection Based on the Biopharmaceutics Classification System

GE Amidon, X He, MJ Hageman - Burger's Medicinal Chemistry …, 2003 - Wiley Online Library
Identifying an active lead molecule, selecting a viable drug candidate and developing a
marketable product are profoundly influenced by molecular properties and dosage form …

[引用][C] Pharmacokinetics: effects of food and fasting. Encyclopedia entry

R Krishna, BK Jensen - Encyclopedia of Pharmaceutical Technology, 2nd edn …, 2003

[引用][C] A NANOPARTICLE ENGINEERING PROCESS: SPRAY-FREEZING INTO LIQUID TO ENHANCE THE DISSOLUTION OF POORLY WATER SOLUBLE DRUGS

AB Combs, JW McGinity