Leptin in the CNS: much more than a satiety signal

J Harvey, MLJ Ashford - Neuropharmacology, 2003 - Elsevier
The discovery of the obese gene product, leptin has generated enormous interest in how the
periphery signals the status of nutritional stores to specific hypothalamic nuclei involved in …

Novel actions of leptin in the hippocampus

J Harvey - Annals of medicine, 2003 - Taylor & Francis
It is well established that the obese gene product, leptin is an important circulating satiety
factor that signals nutritional status to specific hypothalamic nuclei involved in body weight …

Insulin inhibits rat hippocampal neurones via activation of ATP-sensitive K+ and large conductance Ca2+-activated K+ channels

D O'Malley, LJ Shanley, J Harvey - Neuropharmacology, 2003 - Elsevier
In this study, we have used a combination of immunocytochemical and Ca2+ imaging
techniques to determine the functional localisation of insulin receptors as well as the …