[HTML][HTML] Plasmodium biology: genomic gleanings
The highly A+ T rich genomes of human and rodent malarial parasites offer unprecedented
glimpses of a lineage that is distinct from other model organisms. Plasmodium is …
glimpses of a lineage that is distinct from other model organisms. Plasmodium is …
A model for statistical significance of local similarities in structure
Structural biology can provide three-dimensional structures for proteins of unknown function.
When sequence or structure comparisons fail to suggest a function, insights can come from …
When sequence or structure comparisons fail to suggest a function, insights can come from …
Database resources of the National Center for Biotechnology
DL Wheeler, DM Church, S Federhen… - Nucleic acids …, 2003 - academic.oup.com
In addition to maintaining the GenBank (R) nucleic acid sequence database, the National
Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources …
Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources …
[HTML][HTML] Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes
V Anantharaman, L Aravind - Genome biology, 2003 - Springer
Background Peptidoglycan is hydrolyzed by a diverse set of enzymes during bacterial
growth, development and cell division. The N1pC/P60 proteins define a family of cell-wall …
growth, development and cell division. The N1pC/P60 proteins define a family of cell-wall …
Comparative protein structure modeling by iterative alignment, model building and model assessment
Comparative or homology protein structure modeling is severely limited by errors in the
alignment of a modeled sequence with related proteins of known three‐dimensional …
alignment of a modeled sequence with related proteins of known three‐dimensional …
Automated prediction of CASP‐5 structures using the Robetta server
D Chivian, DE Kim, L Malmström… - Proteins: Structure …, 2003 - Wiley Online Library
Robetta is a fully automated protein structure prediction server that uses the Rosetta
fragment‐insertion method. It combines template‐based and de novo structure prediction …
fragment‐insertion method. It combines template‐based and de novo structure prediction …
Three monophyletic superfamilies account for the majority of the known glycosyltransferases
J Liu, A Mushegian - Protein Science, 2003 - Wiley Online Library
Sixty‐five families of glycosyltransferases (EC 2.4. xy) have been recognized on the basis of
high‐sequence similarity to a founding member with experimentally demonstrated …
high‐sequence similarity to a founding member with experimentally demonstrated …
[HTML][HTML] Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the …
Background The eukaryotic RNA-dependent RNA polymerase (RDRP) is involved in the
amplification of regulatory microRNAs during post-transcriptional gene silencing. This …
amplification of regulatory microRNAs during post-transcriptional gene silencing. This …
COMPASS: a tool for comparison of multiple protein alignments with assessment of statistical significance
R Sadreyev, N Grishin - Journal of molecular biology, 2003 - Elsevier
We present a novel method for the comparison of multiple protein alignments with
assessment of statistical significance (COMPASS). The method derives numerical profiles …
assessment of statistical significance (COMPASS). The method derives numerical profiles …