Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer

CM John, H Leffler, B Kahl-Knutsson, I Svensson… - Clinical cancer …, 2003 - AACR
Purpose: The goal of this research was to evaluate a potential therapeutic agent for breast
cancer based on galectin-3 that has been implicated in tumorigenicity and metastasis of …

Malignant transformation of thyroid follicular cells by galectin-3

Y Takenaka, H Inohara, T Yoshii, K Oshima… - Cancer letters, 2003 - Elsevier
Galectin-3, a β-galactoside binding lectin, is highly expressed in thyroid carcinomas of
follicular cell origin, whereas neither benign thyroid adenomas nor normal thyroid tissues …

The investigation of galectin-3 in diseases of the thyroid gland

RB Kovács, J Földes, G Winkler… - European journal of …, 2003 - academic.oup.com
Objective Malignant tumors of the thyroid gland exhibit a variety of histopathologies and
clinical behavior. Immune markers are gaining more and more importance in diagnostic …

Reconstitution of galectin-3 alters glutathione content and potentiates TRAIL-induced cytotoxicity by dephosphorylation of Akt

YJ Lee, YK Song, JJ Song, RR Siervo-Sassi… - Experimental cell …, 2003 - Elsevier
We investigated the role of galectin-3 in tumor necrosis factor-related apoptosis-inducing
ligand (TRAIL)-induced apoptotic death in human breast carcinoma BT549 cells. We …

[HTML][HTML] Wheat gliadin induces apoptosis of intestinal cells via an autocrine mechanism involving Fas–Fas ligand pathway

C Giovannini, P Matarrese, B Scazzocchio, R Varı̀… - FEBS letters, 2003 - Elsevier
Wheat gliadin and other cereal prolamins have been said to be involved in the pathogenic
damage of the small intestine in celiac disease via the apoptosis of epithelial cells. In the …

Novel mechanism that Trypanosoma cruzi uses to adhere to the extracellular matrix and host cells-mediated by human galectin-3

T Moody - 2003 - search.proquest.com
A Dissertation Page 1 NOVEL, MECHANISMI THLAT TRYPANOSOMA CRUZI USES TO
ADHERE TO THE EXTRACETIULAR. NIAFIRTX AND HOST CELTS-MIEDTATED BY HUMANI …