Axonal degeneration has been identified as the major determinant of irreversible
neurological disability in patients with multiple sclerosis (MS). Axonal injury begins at …

The nuclei of the thalamus have traditionally been delineated by their distinct cyto/
myeloarchitectural appearance on histology. Here, we show that diffusion tensor magnetic …

The present study examined patterns of cerebral activation during a working memory (WM)
rehearsal task in individuals diagnosed with multiple sclerosis (MS) and in healthy adults …

ABSTRACT Background and Purpose. Injury to deep gray matter structures in multiple
sclerosis (MS) has been suggested by recent neuroimaging and neuropathology studies …

Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is an inherited small-vessel disease caused by mutations …

Publisher Summary This chapter focuses on cognition and mood disorders.
Neuropsychiatric manifestations commonly occur and are well described in patients with …

Perfusion is a fundamental biological function, giving an indication of tissue metabolism,
through the rate of blood supply. Changes in perfusion accompany almost all forms of brain …

Perfusion is a measure of blood supply to a tissue. The term is used to describe the volume
of blood passing through an organ normalised to the mass of the organ. It is an important …